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2-(Bromodifluoromethyl)-1,3-benzoxazole, also known as BDFBO, is a chemical compound with the molecular formula C8H4BrF2NO. It is a benzoxazole derivative featuring a difluoromethyl bromide group attached to the 2-position of the benzoxazole ring. BDFBO is recognized for its versatility in organic synthesis and its value as an intermediate in the preparation of pharmaceutical compounds and agrochemicals. Its unique structure has garnered interest in medicinal chemistry for its potential as a pharmacological agent for treating various diseases, as well as in the development of novel materials and fluorescent probes for biological imaging.

186828-50-2

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186828-50-2 Usage

Uses

Used in Pharmaceutical Industry:
2-(Bromodifluoromethyl)-1,3-benzoxazole is used as a building block in the synthesis of pharmaceutical compounds for its potential as a pharmacological agent. Its unique structure allows for the development of new drugs that can target a range of diseases, enhancing treatment options and improving patient outcomes.
Used in Agrochemical Industry:
BDFBO serves as an intermediate in the preparation of agrochemicals, contributing to the development of effective and environmentally friendly solutions for pest control and crop protection. Its versatility in organic synthesis enables the creation of novel agrochemicals with improved efficacy and reduced environmental impact.
Used in Material Science:
2-(Bromodifluoromethyl)-1,3-benzoxazole is utilized in the development of novel materials due to its unique chemical properties. Its incorporation into various materials can lead to the creation of new products with enhanced performance characteristics, such as improved stability, reactivity, or selectivity.
Used in Fluorescent Probes for Biological Imaging:
BDFBO has been studied for its use in the production of fluorescent probes for biological imaging applications. Its unique structure allows for the development of probes that can selectively label and visualize specific biological targets, providing valuable insights into cellular processes and aiding in the study of disease mechanisms.

Check Digit Verification of cas no

The CAS Registry Mumber 186828-50-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,6,8,2 and 8 respectively; the second part has 2 digits, 5 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 186828-50:
(8*1)+(7*8)+(6*6)+(5*8)+(4*2)+(3*8)+(2*5)+(1*0)=182
182 % 10 = 2
So 186828-50-2 is a valid CAS Registry Number.
InChI:InChI=1/C8H4BrF2NO/c9-8(10,11)7-12-5-3-1-2-4-6(5)13-7/h1-4H

186828-50-2SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-[bromo(difluoro)methyl]-1,3-benzoxazole

1.2 Other means of identification

Product number -
Other names 2-bromodifluoromethylbenzooxazole

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:186828-50-2 SDS

186828-50-2Relevant academic research and scientific papers

A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles and its application in the synthesis of gem-difluoromethylene linked aryl ether compounds

Jiang, Haizhen,Yuan, Shijie,Cai, Yeshan,Wan, Wen,Zhu, Shizheng,Hao, Jian

experimental part, p. 167 - 170 (2012/02/04)

A facile preparation of 2-bromodifluoromethyl benzo-1,3-diazoles as novel CF2Br-containing heterocyclic building blocks has been developed through a one-pot process of reaction of 2-OH, 2-SH, or 2-NH2 substituted aniline with bromodifluoroacetic acid in the presence of 3 molar equivalents of CBr4 and Ph3P in refluxing toluene. 2-Bromodifluoromethyl benzo-1,3-thiazole (2b) was successfully utilized in the preparation of gem-difluoromethylene linked aryl ether compounds through the reaction with phenolates or thiophenolate in DMF in good yields.

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