18781-72-1

Usage

Uses

Used in Pharmaceutical Industry:
2,3,4,4a-Tetrahydro-4a-methyl-1H-carbazole is used as a key intermediate in the synthesis of new drugs for various therapeutic applications. Its unique structure allows for the development of innovative pharmaceutical compounds with potential biological and pharmacological activities.
Used in Agrochemical Industry:
In the agrochemical industry, 2,3,4,4a-Tetrahydro-4a-methyl-1H-carbazole is utilized as a precursor for the synthesis of pesticides and herbicides. Its chemical properties enable the creation of effective and targeted agrochemicals for crop protection and management.
Used in Medicinal Chemistry Research:
2,3,4,4a-Tetrahydro-4a-methyl-1H-carbazole is also used as a compound of interest in the field of medicinal chemistry. Its potential biological and pharmacological activities are being studied to explore its applications in drug discovery and development, contributing to the advancement of novel therapeutic agents.

Upstream product

• 64-19-7 acetic acid 
• 1208-57-7 2-methylcyclohexanone phenylhydrazone 
• 854715-10-9 cyclohexanone-o-tolylhydrazone 
• 109-99-9 tetrahydrofuran 
• 60-29-7 diethyl ether 
• 917-54-4 methyllithium 
• 4669-18-5 spiro[cyclopentane-1,2'-indolin]-3'-one 
• 64-17-5 ethanol 
• 5435-44-9 (E)-3-Ureido-but-2-enoic acid ethyl ester 
• 942-01-8 1,2,3,4-tetrahydrocarbazole 
• 74-88-4 methyl iodide 
• 583-60-8 2-Methylcyclohexanone 
• 100-63-0 phenylhydrazine 
• 7647-01-0 hydrogenchloride 

Downstream Products

• 41503-36-0 2,3,4,4a-Tetrahydro-4a,9-dimethylcarbazol 
• 84196-42-9 1-<2-(p-Methoxybenzoyl)vinyl>-4a,9-dimethyl-2,3,4,4a-tetrahydrocarbazole 
• 84196-40-7 1-<2-(p-Nitrobenzoyl)vinyl>-4a,9-dimethyl-2,3,4,4a-tetrahydrocarbazole 
• 89228-50-2 Acetic acid 2-(1-methyl-2-oxo-cyclohexyl)-phenyl ester 
• 53155-53-6 (+/-)-9-benzoyl-4a-methyl-(4ar,9ac)-1,2,3,4,4a,9a-hexahydro-carbazole 
• 1385798-18-4 C₂₀H₂₃N 
• 1385798-20-8 C₂₀H₂₂BrN 
• 1385798-22-0 C₂₆H₃₄BNO₂ 
• 1446741-29-2 C₂₆H₂₆BrN 
• 1446741-30-5 C₃₂H₃₈BNO₂ 

Relevant academic research and scientific papers

A sterically hindered optically active pentamethine dye

Bis[1,3-dimethyl-3,8-(trimethylen)-indolinyl]pentamethinium iodide (5) was synthesized by coupling rac 4a-methyl-2,3,4,4a-tetrahydro-1H-carbazole (3) with 1,1,3,3-tetraethoxypropane. The configuration of the dye is 2Z,8E,9E,10E,9′E,8′Z as shown by 1H NMR spectroscopy. Starting with the enantiomerically pure carbazole (95% e.e.) the optically active pentamethine 5a was obtained in 84% optical yield. The CD absorption of 5a at 653 nm indicates a significant helical distortion of the chromophore.

An indoxyl-based strategy for the synthesis of indolines and indolenines

An indoxyl-based strategy for the synthesis of indolines and indolenines via unprecedented aza-pinacol and aza-semipinacol rearrangements was developed. This method provides direct access to the core structures of several classes of indole alkaloids. The synthetic utility was demonstrated by the divergent synthesis of an array of functionalized polycyclic structures from a common intermediate and the formal total synthesis of the indoline natural product minfiensine. The reversed reactivity of indoxyl as a building block compared to that of indole offers a conceptually distinct disconnection strategy for indoline- and indolenine-containing heterocycles and natural products. Making other arrangements: The chemical synthesis of a diverse range of functionalized indolines/indolenines and the formal total synthesis of the indoline natural product minfiensine were achieved by using an indoxyl-based strategy that proceeds via unprecedented aza-pinacol rearrangements. This method provides direct access to the core structures of several classes of indole alkaloids by employing conceptually distinct bond disconnections.

Potential inhibitors of tyrosine hydroxylase and dopamine-β-hydroxylase

A series of methyl-substituted 1,2,3,4-tetrahydrocarbazoles was synthesized and screened for in vitro activity against tyrosine hydroxylase and dopamine-β-hydroxylase. The most potent compounds were evaluated for inhibition of norepinephrine biosynthesis in rats. The results indicated no significant decrease in norepinephrine levels at three dosage levels.

Organic light-emitting diode having alleviated luminance reduction in low dynamic range

The present disclosure relates to an organic light-emitting diode which can operate at a low voltage with high efficiency and exhibits the effect of having an alleviated luminance reduction rate in a low dynamic range. More particularly, the organic light-emitting diode comprises: a first electrode; a second electrode facing the first electrode; and a light-emitting layer and a charge balance control layer arranged sequentially between the first and the second electrode, wherein the light-emitting layer includes at least one of amine derivative compounds represented by the following Chemical Formula A and the charge balance control layer includes at least one of anthracene derivative compounds represented by the following Chemical Formula B or C. The structures of Chemical Formulas A, B, and C are as defined in the specification.

An electroluminescen compound and an electroluminescent device comprising the same

The present invention relates to an organic light-emitting compound represented by chemical formula 1. An organic electroluminescent device comprising the organic light-emitting compound in the present invention has excellent power efficiency, light-emitting efficiency, and long life cycle because the present invention can be operated by a lower driving-voltage in comparison to a device comprising conventional phosphorescent host materials. [Chemical formula 1].

Novel boron compounds and Organic light emitting diode including the same

The present invention relates to a boron compound usable in an organic light-emitting device, and an organic light-emitting device comprising the same and, more particularly, to a boron compound represented by any one of chemical formula A to chemical formula D and an organic light-emitting device comprising the same. The chemical formula A to chemical formula D are the same as described in the detailed description of the invention. When the novel boron compound is used as a dopant material in an organic light-emitting device, the organic light-emitting device exhibits longer life characteristics compared to the prior art.

Novel boron compounds and Organic light emitting diode including the same

The present invention relates to a boron compound that can be used in an organic light-emitting element, and an organic light-emitting element comprising same, and more specifically, to a boron compound represented by [chemical formula A] and an organic l

Boron compound and organic light emitting diode including the same

Disclosed herein are a boron compound available for an organic light-emitting diode and an organic light-emitting diode including same. More particularly, a boron compound represented by Chemical Formula A and an organic light-emitting diode including sam

An electroluminescent compound and an electroluminescent device comprising the same

The present invention relates to an organic light-emitting compound represented by [Chemical formula 1]. An organic electroluminescent device comprising the organic light-emitting compound in the present invention has excellent power efficiency, light-emitting efficiency, and long life cycle because the present invention can be operated by a lower driving-voltage in comparison with a device comprising conventional phosphorescent host materials. [Chemical formula 1].

Deuterated organic compounds for organic light-emitting diode and organic light-emitting diode including the same

The present invention relates to an organic electroluminescent compound represented by chemical formula A and an organic light emitting device comprising the same. Substituents Y, Ar2 , L3 , K, p and x are as defined in the description of the invention. [Chemical A] (by machine translation)