188255-33-6Relevant academic research and scientific papers
Synthesis of an isochroman analogue of the michellamines
De Koning, Charles B.,Michael, Joseph P.,Van Otterlo, Willem A.L.
, p. 3037 - 3040 (1999)
The synthesis of racemic 5-iodo-6,8-dimethoxy-1,3-trans- dimethylisochroman (16) in eleven steps from 2,4-dimethoxybenzaldehyde is outlined. Compound (16) was coupled by means of Suzuki methodology with 4- isopropoxy-5-methoxy-7-methylnaphthaleneboronic a
Syntheses of isochromane analogues of the michellamines and korupensamines
De Koning, Charles B.,Michael, Joseph P.,Van Otterlo, Willem A.L.
, p. 799 - 811 (2007/10/03)
Syntheses of the oxygen analogues 6, 7 and 8 of the michellamines 1 and korupensamines 2 are described. Racemic 5-iodo-6,8-dimethoxy-trans-1,3-dimethylisochromane 10 was synthesised in eleven steps from 2,4-dimethoxybenzaldehyde in an overall yield of 51%
