18920-70-2Relevant articles and documents
Liquid-Phase Total Synthesis of Plecanatide Aided by Diphenylphosphinyloxyl Diphenyl Ketone (DDK) Derivatives
Chang, Ninghui,Chao, Jie,Li, Haidi,Li, Jun,Qin, Chuanguang,Tian, Guang,Zhang, Zixin
, p. 3323 - 3328 (2020/04/20)
Plecanatide is an oral guanylate cyclase-C agonist for the treatment of gastrointestinal disorders. The large-scale supply of plecanatide is restrained primarily by its industrial manufacture. Herein we developed diphenylphosphinyloxyl diphenyl ketone (DD
INDENE DERIVATIVES USEFUL IN TREATING PAIN AND INFLAMMATION
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, (2019/10/29)
Compounds of formula (I): wherein,R1, R2, R3, R4a, R4b and R5 are described herein, or a stereoisomer, enantiomer or tautomer thereof or mixtures thereof, or a pharmaceutically acceptable s
Design and synthesis of norendoxifen analogues with dual aromatase inhibitory and estrogen receptor modulatory activities
Lv, Wei,Liu, Jinzhong,Skaar, Todd C.,Flockhart, David A.,Cushman, Mark
, p. 2623 - 2648 (2015/04/14)
Both selective estrogen receptor modulators and aromatase inhibitors are widely used for the treatment of breast cancer. Compounds with both aromatase inhibitory and estrogen receptor modulatory activities could have special advantages for treatment of br