189746-21-2

Usage

Uses

Used in Pharmaceutical Industry:
5-CHLORO-2,6-DIMETHOXY-4-METHYL-8-NITROQUINOLINE is used as a pharmaceutical agent for its potential medicinal properties. The presence of various functional groups allows for the possibility of it being developed into a drug candidate with specific therapeutic effects.
Used in Dye Industry:
5-CHLORO-2,6-DIMETHOXY-4-METHYL-8-NITROQUINOLINE is used as a dye due to the presence of chromophoric groups, such as the nitro and chloro groups, which can impart color to various substrates.
Used in Pesticide Industry:
5-CHLORO-2,6-DIMETHOXY-4-METHYL-8-NITROQUINOLINE is used as a pesticide, leveraging its chemical structure to potentially target and control pests, thanks to the presence of functional groups that may have biocidal properties.
Used in Industrial Chemicals:
5-CHLORO-2,6-DIMETHOXY-4-METHYL-8-NITROQUINOLINE is used as an industrial chemical for various applications, such as in the synthesis of other compounds or as an intermediate in chemical processes, due to its complex and versatile molecular structure.

InChI:InChI=1/C12H11ClN2O4/c1-6-4-9(19-3)14-12-7(15(16)17)5-8(18-2)11(13)10(6)12/h4-5H,1-3H3

Upstream product

• 337913-25-4 phosphorus pentaoxide 
• 189746-19-8 5-chloro-2,6-dimethoxy-4-methyl-quinoline 
• 78-40-0 triethyl phosphate 
• 110-54-3 hexane 
• 189746-20-1 2,6-dimethoxy-4-methyl-quinoline 
• 6340-55-2 2-chloro-4-methyl-6-methoxyquinoline 

Downstream Products

• 1260253-76-6 8-amino-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenyl)-quinoline 
• 1260253-77-7 8-amino-2,6-dimethoxy-4-methyl-5-(4-trifluoromethylphenyl)-quinoline 
• 1260253-78-8 8-amino-2,6-dimethoxy-5-(3-methoxyphenyl)-4-methyl-quinoline 
• 1260253-79-9 8-amino-2,6-dimethoxy-4-methyl-5-(3-methylphenyl)-quinoline 
• 1260253-80-2 8-amino-5-(3,4-dichlorophenyl)-2,6-dimethoxy-4-methyl-quinoline 
• 1260253-86-8 8-[(1-methyl-4-phthalimido)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(3-trifluoromethyl-phenyl)-quinoline 
• 1260253-87-9 8-[(1-methyl-4-phthalimido)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(4-trifluoromethyl-phenyl)-quinoline 
• 1260253-88-0 8-[(1-methyl-4-phthalimido)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(3-methoxyphenyl)-quinoline 
• 1260253-89-1 8-[(1-methyl-4-phthalimido)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(3-methylphenyl)-quinoline 
• 1260253-90-4 8-[(1-methyl-4-phthalimido)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(3,4-dichlorophenyl)-quinoline 
• 1260253-41-5 8-[(4-amino-1-methyl)-butyl]-amino-2,6-dimethoxy-4-methyl-5-phenyl-quinoline succinate 
• 1260253-47-1 8-[(4-amino-1-methyl)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(3-trifluoromethylphenyl)-quinoline succinate 
• 1260253-49-3 8-[(4-amino-1-methyl)-butyl]-amino-2,6-dimethoxy-4-methyl-5-(4-trifluoromethylphenyl)-quinoline succinate 
• 1260253-51-7 8-[(4-amino-1-methyl)-butyl]-amino-2,6-dimethoxy-5-(3-methoxyphenyl)-4-methylquinoline succinate 

Relevant academic research and scientific papers

Antimalarial activity of novel 5-aryl-8-aminoquinoline derivatives

In an attempt to separate the antimalarial activity of tafenoquine (3) from its hemolytic side effects in glucose-6-phosphate dehydrogenase (G6PD) deficiency patients, a series of 5-aryl-8-aminoquinoline derivatives was prepared and assessed for antimalar

Process for the preparation of anti-malarial drugs

The invention relates to novel intermediates and processes for the preparation of quinoline compounds useful as anti-malarial drugs and novel intermediates useful in the process. A process for the preparation of a compound of formula (I) in which R1is C1-6alkyl; R2and R3are independently hydrogen, halogen, trifluoromethyl or C1-6alkoxy; R4is C1-6alkyl; R5is hydrogen or C1-6alkyl; and R6or amino which comprises reacting a compound of formula (II) in which R1, R4and R5are as defined in formula (I) and X is a leading group with a compound of formula (III).