189747-31-7 Usage
General Description
6-Chloropyrimido[5,4-d]pyrimidin-4(3H)-one is a chemical compound with the molecular formula C8H5ClN4O. It is a heterocyclic compound that contains two fused pyrimidine rings with a chlorine atom and a carbonyl group. 6-Chloropyrimido[5,4-d]pyrimidin-4(3H)-one has potential use in the development of pharmaceuticals and agrochemicals. Its structure and properties make it a valuable building block for the synthesis of various bioactive compounds. It is also used as a precursor in organic synthesis for the preparation of diverse chemical structures. Overall, 6-Chloropyrimido[5,4-d]pyrimidin-4(3H)-one plays an important role in medicinal and chemical research, and its versatile properties make it a valuable compound in various fields of science and industry.
Check Digit Verification of cas no
The CAS Registry Mumber 189747-31-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,8,9,7,4 and 7 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 189747-31:
(8*1)+(7*8)+(6*9)+(5*7)+(4*4)+(3*7)+(2*3)+(1*1)=197
197 % 10 = 7
So 189747-31-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H3ClN4O/c7-6-8-1-3-4(11-6)5(12)10-2-9-3/h1-2H,(H,9,10,12)
189747-31-7Relevant articles and documents
Tyrosine kinase inhibitors. 12. Synthesis and structure-activity relationships for 6-substituted 4-(phenylamino)pyrimido[5,4-d]pyrimidines designed as inhibitors of the epidermal growth factor receptor
Rewcastle, Gordon W.,Bridges, Alexander J.,Fry, David W.,Rubin, J. Ronald,Denny, William A.
, p. 1820 - 1826 (1997)
A series of 6-substituted 4-anilinopyrimido[5,4-d]pyrimidines has been prepared and shown to be potent inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). These compounds are structurally related to the pyrido[3,2-d]
