189747-55-5

Basic information

• Product Name: Pyrimido[5,4-d]pyrimidin-4-amine, 6-chloro-N-(3-methylphenyl)-
• CAS NO: 189747-55-5
• Molecular Formula: C13H10ClN5
• Molecular Weight: 271.709
• Mol File: 189747-55-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyrimido[5,4-d]pyrimidin-4-amine, 6-chloro-N-(3-methylphenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyrimido[5,4-d]pyrimidin-4-amine, 6-chloro-N-(3-methylphenyl)-(189747-55-5)
• EPA Substance Registry System: Pyrimido[5,4-d]pyrimidin-4-amine, 6-chloro-N-(3-methylphenyl)-(189747-55-5)

Safety Data

• Hazardous Substances Data: 189747-55-5(Hazardous Substances Data)

Upstream product

• 189747-31-7 6-chloropyrimido[5,4-d]pyrimidin-4(3H)-one 
• 189747-29-3 5-amino-2-chloropyrimidine-4-carboxamide 
• 59950-50-4 ethyl 5-amino-2-chloropyrimidine-4-carboxylate 
• 108-44-1 1-amino-3-methylbenzene 
• 189747-34-0 2,8-dichloropyrimido(5,4-d)pyrimidine 

Relevant articles and documents

Tyrosine kinase inhibitors. 12. Synthesis and structure-activity relationships for 6-substituted 4-(phenylamino)pyrimido[5,4-d]pyrimidines designed as inhibitors of the epidermal growth factor receptor

A series of 6-substituted 4-anilinopyrimido[5,4-d]pyrimidines has been prepared and shown to be potent inhibitors of the tyrosine kinase activity of the epidermal growth factor receptor (EGFR). These compounds are structurally related to the pyrido[3,2-d]