19036-99-8

Basic information

• Product Name: (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene
• Synonyms: (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene;2-[(E)-2-(4-Methoxyphenyl)ethenyl]pyridine;(E)-2-(4-Methoxystyryl)pyridine
• CAS NO: 19036-99-8
• Molecular Formula: C₁₄H₁₃NO
• Molecular Weight: 211.26
• Mol File: 19036-99-8.mol
• Article Data: 17

Chemical Properties

• Melting Point: 98-100 °C
• Boiling Point: 354.2±11.0 °C(Predicted)
• Appearance: /
• Density: 1.112±0.06 g/cm3(Predicted)
• PKA: 4.71±0.10(Predicted)
• CAS DataBase Reference: (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene(CAS DataBase Reference)
• NIST Chemistry Reference: (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene(19036-99-8)
• EPA Substance Registry System: (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene(19036-99-8)

Safety Data

• Hazardous Substances Data: 19036-99-8(Hazardous Substances Data)

Usage

General Description

(E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene, also known as 2-(4-Methoxyphenyl)-1-(2-pyridyl)ethene or trans-4'-methoxystilbene, is a chemical compound with the molecular formula C17H15NO. It is a derivative of stilbene, a type of organic compound that contains a central ethene double bond and two aromatic rings. The compound is commonly used in organic synthesis and pharmaceutical research due to its potential biological activity, including its ability to inhibit the growth of cancer cells. It is also studied for its potential antioxidant and anti-inflammatory properties. Additionally, (E)-1-(4-Methoxyphenyl)-2-(2-pyridyl)ethene has been investigated for its potential use as a fluorescent probe in biochemical and biomedical studies.

Upstream product

• 73853-36-8 2-<2-Hydroxy-2-(-p-methoxyphenyl)ethyl>pyridine 
• 110-86-1 pyridine 
• 100-69-6 2-vinylpyridine 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 100-66-3 methoxybenzene 
• 931-19-1 2-methylpyridine N-oxide 
• 105-13-5 4-Methoxybenzyl alcohol 
• 694-59-7 pyridine N-oxide 
• 38700-15-1 triphenyl-(2-pyridylmethyl)phosphonium chloride 
• 123-11-5 4-methoxy-benzaldehyde 
• 5720-07-0 4-methoxyphenylboronic acid 
• 99662-46-1 triphenyl(pyridin-2-ylmethyl)phosphonium chloride hydrochloride 
• 99-96-7 4-hydroxy-benzoic acid 
• 824-94-2 p-methoxybenzyl chloride 

Downstream Products

• 1251668-19-5 2-(2,2-di(4-methoxyphenyl)vinyl)pyridine 
• 71413-38-2 RhBr₂(P((CH₂)3CH₃)3)2(C₅H₄NCHC(C₆H₄OCH₃)) 
• 77377-07-2 (E)-4-(2-(pyridin-2-yl)vinyl)phenol 
• 26573-47-7 1-[2-(4-methoxy-phenyl)-indolizin-3-yl]-ethanone 

Relevant articles and documents

A new insight into the push-pull effect of substituents via the stilbene-like model compounds

In this paper, authors report on 1-pyridyl-2-arylethenes, 1-furyl-2-arylethylenes, 1,2-diphenylpropylenes and substituted cinnamyl anilines as stilbene-like model compounds to investigate the factors dominating the push-pull effect of substituents via usi

Determination and application of the excited-state substituent constants of pyridyl and substituted phenyl groups

Thirty six 1-pyridyl-2-arylethenes XCH=CHArY (abbreviated XAEY) were synthesized, in which, X is 2-pyridyl, 3-pyridyl and 4-pyridyl and Y is OMe, Me, H, Br, Cl, F, CF3, and CN. Their ultraviolet absorption spectra were measured in anhydrous ethanol, and their wavelengths of absorption maximum λmax were recorded. Also, the 234 λmax values of 1-substituted phenyl-2-arylethylene compounds (XAEY, where X is substituted phenyl) were collected. The excited-state substituent constants (Formula presented.) of three pyridyl groups and 23 substituted phenyl groups (total of 26) were obtained by means of curve-fitting method. Taking the λmax values of 358 samples of bi-arylethene derivatives as a data set and 126 samples of bi-aryl Schiff bases (including nine compounds synthesized by this work) as another data set, quantitative correlation analyses were performed by employing the obtained (Formula presented.) as a parameter, and good results were obtained for the two data sets. The reliability of the obtained (Formula presented.) values was verified. The results of this paper can provide excited-state substituent constants for the study and application of optical properties of conjugated organic compounds containing aryl groups.

Iron-Catalyzed Coupling of Methyl N-Heteroarenes with Primary Alcohols: Direct Access to E-Selective Olefins

An efficient Fe-catalyzed system is reported for direct α-olefination of methyl-substituted N-heteroarenes with primary alcohols. The catalytic dehydrogenative coupling enables a series of functionalized E-olefinated N-heteroaromatics with excellent selectivity (>99%). Initial mechanistic studies including deuterium-labeling experiments provide evidence for the participation of the benzylic C-H/D bond of alcohols.