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α-Bromophenylacetic acid N,N-diethylamide is an organic compound with the chemical formula C11H16BrNO. It is a derivative of α-bromophenylacetic acid, where the carboxylic acid group is amide-ified with two ethylamine groups. This results in a molecule that has a bromine atom attached to a phenyl ring, a two-carbon chain, and two ethylamine groups attached to the nitrogen atom. The compound is known for its potential applications in the synthesis of various pharmaceuticals and agrochemicals, particularly as an intermediate in the production of certain drugs. It is also recognized for its role in chemical research, where it can be used to study the effects of structural modifications on molecular properties and reactivity.

91801-96-6

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91801-96-6 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 91801-96-6 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 9,1,8,0 and 1 respectively; the second part has 2 digits, 9 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 91801-96:
(7*9)+(6*1)+(5*8)+(4*0)+(3*1)+(2*9)+(1*6)=136
136 % 10 = 6
So 91801-96-6 is a valid CAS Registry Number.

91801-96-6Relevant articles and documents

The discovery and synthesis of JNJ 31020028, a small molecule antagonist of the Neuropeptide y Y2 receptor

Swanson, Devin M.,Wong, Victoria D.,Jablonowski, Jill A.,Shah, Chandra,Rudolph, Dale A.,Dvorak, Curt A.,Seierstad, Mark,Dvorak, Lisa K.,Morton, Kirsten,Nepomuceno, Diane,Atack, John R.,Bonaventure, Pascal,Lovenberg, Timothy W.,Carruthers, Nicholas I.

scheme or table, p. 5552 - 5556 (2011/10/12)

A series of small molecules based on a chemotype identified from our compound collection were synthesized and tested for binding affinity (IC 50) at the human Neuropeptide Y Y2 receptor (NPY Y 2). Six of the 23 analogs tes

Carbon-carbon bond-forming reactions of α-carbonyl carbocations: Exploration of a reversed-polarity equivalent of enolate chemistry

Lai, Ping-Shan,Dubland, Joshua A.,Sarwar, Mohammed G.,Chudzinski, Michael G.,Taylor, Mark S.

supporting information; experimental part, p. 7586 - 7592 (2011/10/12)

Carbon-carbon bond-forming reactions of putative α-carbonyl carbocation intermediates generated by Lewis acid- or silver-promoted ionizations of toluenesulfonate or halide leaving groups are described. This under-exploited mode of reactivity represents an 'umpolung' of conventional enolate chemistry, and enables C-C bond construction in both intra- and intermolecular contexts. Attempts to develop diastereoselective variants of this process using chiral ester and oxazolidinone-based auxiliaries are discussed.

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

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Page/Page column 33, (2009/03/07)

The present invention is directed to piperazinyl derivatives useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of said compounds for the treatment and / or prevention of disorders, diseases and conditions mediated by the NPY Y2 receptor.

SUBSTITUTED PIPERAZINES AND PIPERIDINES AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

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Page/Page column 27, (2010/11/27)

The invention provides novel non-peptidic NPY Y2 receptor inhibitors useful in treating or preventing: anxiolytic disorders or depression; injured mammalian nerve tissue; conditions responsive to treatment through administration of a neurotrophic factor; neurological disorders; bone loss; substance related disorders; sleep/wake disorders; cardiovascular disease; obesity; or an obesity-related disorder. Compounds of the invention are also useful in modulating endocrine functions, particularly endocrine functions controlled by the pituitary and hypothalamic glands, and are therefore useful in the treatment or prevention of inovulation and infertility.

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