191031-07-9

Upstream product

• 135-13-7 (o-carboxyphenyl)thioacetic acid 
• 40142-71-0 3-amino-benzo[b]thiophene-2-carboxylic acid 
• 16671-86-6 2-thiocyanatobenzoic acid 
• 394-35-4 methyl 2-fluorobenzoate 
• 4892-02-8 Methyl thiosalicylate 
• 6287-88-3 methyl 2-[(2-methoxy-2-oxoethyl)thio]benzoate 
• 13134-76-4 methyl 3-hydroxybenzo[b]thiophene-2-carboxylate 
• 147-93-3 Thiosalicylic acid 
• 98589-44-7 (2-cyano-phenylsulfanyl)-acetic acid 
• 127-09-3 sodium acetate 
• 108-24-7 acetic anhydride 

Downstream Products

• 6424-61-9 3-(3-oxo-3H-benzo[b]thiophen-2-ylidene)-1,3-dihydro-indol-2-one 
• 6252-78-4 2-(2-oxo-acenaphthen-1-ylidene)-benzo[b]thiophen-3-one 
• 36540-15-5 2-phenylazo-benzo[b]thiophen-3-ol 
• 243-68-5 benzo[4,5]thieno[3,2-b]quinoline 
• 92424-67-4 2-(2-nitro-benzylidene)-benzo[b]thiophen-3-one 
• 520-72-9 3-hydroxybenzothiophene 
• 15719-64-9 methylammonium carbonate 
• 130-03-0 thioindoxyl 
• 3844-31-3 trans-thioindigo 
• 24434-82-0 benzo[b]thiophen-3-yl acetate 
• 6406-15-1 9-chloro-2-(3-oxo-3H-benzo[b]thiophen-2-ylidene)-naphtho[2,3-b]thiophen-3-one 

Relevant academic research and scientific papers

METHOD FOR PROMOTING PLANT GROWTH

The present invention provides a method for promoting plant growth, which comprises treating a plant with at least one compound selected from a group consisting of a compound represented by the following Formula (1): and an agriculturally acceptable salt thereof, provided that a method for promoting plant growth which comprises treating plants with a compound corresponding to any one of the following (1) to (5) and an agriculturally acceptable salt thereof is excluded: (1) 4-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (2) 5-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (3) 6-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, (4) 7-(Trifluoromethyl)benzo[b]thiophene-2-carboxylic acid, and (5) Benzo[b]thiophene-2-carboxylic acid.

Efficient synthesis and 5-LOX/COX-inhibitory activity of some 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives

A series of 3-hydroxybenzo[b]thiophene-2-carboxylic acid derivatives has been prepared and subsequently evaluated with regards to the inhibition of 5-LOX/COX. Structure optimization furnished derivatives with promising in vitro activity as dual 5-LOX/COX inhibitors with submicromolar IC50 values for inhibition of 5-LOX and COX-1, respectively.