37517-78-5

Basic information

• Product Name: Magnesium ethyl malonate
• Synonyms: Magnesium ethyl malonate;Magnesium bis(ethyl malonate;Magnesium 3-ethoxy-3-oxopropanoate
• CAS NO: 37517-78-5
• Molecular Formula: 2C₅H₇O₄*Mg
• Molecular Weight: 286.51836
• EINECS: -0
• Product Categories: Grignard Reagent
• Mol File: 37517-78-5.mol
• Article Data: 15

Chemical Properties

• Boiling Point: 132 °C(Press: 20 Torr)
• Appearance: /
• CAS DataBase Reference: Magnesium ethyl malonate(CAS DataBase Reference)
• NIST Chemistry Reference: Magnesium ethyl malonate(37517-78-5)
• EPA Substance Registry System: Magnesium ethyl malonate(37517-78-5)

Safety Data

• Hazardous Substances Data: 37517-78-5(Hazardous Substances Data)

Usage

General Description

Magnesium ethyl malonate is a compound formed from the reaction of magnesium with ethyl malonate. It is a crystalline solid with a chemical formula of C8H12MgO8 and a molecular weight of 268.5 g/mol. Magnesium ethyl malonate is often used as a reagent in organic chemistry synthesis, particularly in the formation of carbon-carbon bonds. It can also be used as a source of magnesium in various chemical reactions. Additionally, magnesium ethyl malonate has potential applications in the pharmaceutical industry for the synthesis of bioactive compounds. Overall, this compound plays a significant role in organic synthesis and has the potential for various industrial and pharmaceutical applications.

Upstream product

• 105-53-3 diethyl malonate 
• 6148-64-7 ethyl potassium malonate 
• 1071-46-1 hydrogen ethyl malonate 
• 2414-98-4 magnesium ethylate 

Downstream Products

• 129374-48-7 ethyl 5-(4,5-diphenyl-2-oxazolyl)pentan-3-onate 
• 81581-27-3 ethyl 3-(benzo[d][1,3]dioxol-5-yl)-3-oxopropanoate 
• 383663-81-8 ethyl 3-(2-methyl-5-nitrophenyl)-3-oxopropionate 
• 182492-41-7 3-Oxo-4-(2-naphthyl)-butanoic acid ethyl ester 
• 136774-71-5 Ethyl 3-acetamido-2,4-dichloro-β-oxobenzenepropanoate 
• 122858-46-2 ethyl 4-(1-acetyl-1,2,3,6-tetrahydro-pyridin-4-yl)-2,5-difluoro-β-oxobenzenepropionate 
• 122858-13-3 ethyl 4-(1-acetyl-4-piperidinyl)-2,5-difluoro-β-oxobenzenepropionate 
• 105152-55-4 ethyl 2-[2-(2,4-difluorophenylamino)-5-fluoro-6-hydroxynicotinoyl]acetate 
• 1351987-26-2 (S)-1-benzyl-6-ethyl-2-isopropyl-4-oxohexanedioate 
• 1351987-25-1 (S)-ethyl-5-(((S)-4-benzyloxazolidin-2-on-3-yl)carbonyl)-6-methyl-3-oxoheptanoate 
• 1621585-98-5 ethyl 3-[(4aR,6R,8aS)-2-(benzoylamino)-8a-(2,4-difluorophenyl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-6-yl]-3-oxopropanoate 
• 1607025-04-6 ethyl 3-(1-ethyl-1H-indazol-6-yl)-3-oxopropanoate 
• 1607025-02-4 ethyl 3-(1-ethyl-3-methyl-1H-indazol-5-yl)-3-oxopropanoate 
• 1607024-87-2 ethyl 3-(1-isopropyl-1H-indazol-5-yl)-3-oxopropanoate 

Relevant articles and documents

Biosynthesis of a fluorescent protein with extreme Pseudo-stokes shift by introducing a genetically encoded non-natural amino acid outside the fluorophore

A novel kind of fluorescent protein relying on the intramolecular interplay between two different fluorophores, one of chemical origin and one of biological origin, was developed. The fluorescent non-natural amino acid l-(7-hydroxycoumarin-4-yl)ethylglyci

Fluorescent IGF-II analogues for FRET-based investigations into the binding of IGF-II to the IGF-1R

The interaction of IGF-II with the insulin receptor (IR) and type 1 insulin-like growth factor receptor (IGF-1R) has recently been identified as potential therapeutic target for the treatment of cancer. Understanding the interactions of IGF-II with these receptors is required for the development of potential anticancer therapeutics. This work describes an efficient convergent synthesis of native IGF-II and two non-native IGF-II analogues with coumarin fluorescent probes incorporated at residues 19 and 28. These fluorescent analogues bind with nanomolar affinities to the IGF-1R and are suitable for use in fluorescence resonance energy transfer (FRET) studies. From these studies the F19Cou IGF-II and F28Cou IGF-II proteins were identified as good probes for investigating the binding interactions of IGF-II with the IGF-1R and its other high affinity binding partners.

NOVEL COMPOUNDS AS ANTI-MYCOBACTERIALS

The present disclosure relates to antibacterial compounds. In particular, the compounds are for inhibiting the growth of bacteria, particularly Mycobacterium tuberculosis (Mtb), and/or targeting bacteria having phospho-MurNAc-pentapeptidetranslocase. The present disclosure also relates to compositions containing these compounds and methods of the use of these compounds and compositions.

HIGH-SENSITIVE FLUORESCENT ENERGY TRANSFER ASSAY USING FLUORESCENT AMINO ACIDS AND FLUORESENT PROTEINS

The disclosure provides method and composition utilizing fluorescent amino acids and fluorescent proteins comprising a moiety capable of undergoing FRET. The methods and compositions of the disclosure are useful in analyzing protein structure and function