191212-52-9

Upstream product

• 94142-51-5 (3S,5R)-5-Benzyloxymethyl-3-(4-methoxy-phenyl)-3-methyl-dihydro-furan-2-one 
• 223692-13-5 (3S,5R)-5-Benzyloxymethyl-3-(4-methoxy-phenyl)-3-methyl-tetrahydro-furan-2-ol 
• 191212-44-9 (2R,4R)-1-benzyloxy-4-(4-methoxyphenyl)-4-methyl-5-hexen-2-ol 
• 191212-45-0 (2R,4R)-4-(4-methoxyphenyl)-4-methyl-5-hexene-1,2-diol 
• 191212-46-1 (R)-3-(4-methoxyphenyl)-3-methyl-4-pentenal 
• 235101-15-2 ethyl trans-(S)-(+)-4-(4-methoxyphenyl)-4-methylhexa-2,5-dienoate 
• 235101-18-5 methyl (R)-(+)-3-(methoxymethoxy)-2-(4-methoxyphenyl)-2-methylpropionate 
• 235101-25-4 (R)-(+)-3-(methoxymethoxy)-2-(4-methoxyphenyl)-2-methylpropanol 
• 959903-74-3 methyl (R)-(+)-3-hydroxy-2-(4-methoxyphenyl)-2-methylpropionate 
• 235101-20-9 1-Methoxy-4-((R)-1-methoxymethoxymethyl-1-methyl-allyl)-benzene 
• 235101-19-6 (R)-(+)-3-(methoxymethoxy)-2-(4-methoxyphenyl)-2-methylpropanal 
• 235101-21-0 (R)-2-(4-methoxyphenyl)-2-methylbut-3-en-1-ol 
• 235101-22-1 (R)-2-(4-Methoxy-phenyl)-2-methyl-but-3-enal 
• 790260-90-1 (R)-(+)-2-(methoxycarbonyl)-2-(4-methoxyphenyl)propionic acid 

Downstream Products

• 191212-50-7 (R)-1-(3,7-dimethylocta-1,6-dien-3-yl)-4-methoxybenzene 

Relevant academic research and scientific papers

Total synthesis of (-)-sporochnol A, the fish deterrent, from a chiral malonate

From a single chiron, the homochiral benzylic malonic acid ester (R)- (+)-2 available with high enantiomeric excess by enzymatic hydrolysis (PLE acetonic powder), enantiomerically pure (-)-sporochnol A 1 was prepared. This versatile method allows preparation of sporochnol 1, via aldehydes 7 and 15, in good overall yield.

The absolute configuration of (+)-sporochnol A, the fish deterrent from the Caribbean marine alga Sporochnus bolleanus

The absolute configuration of (+)-sporochnol A, the fish deterrent from the Caribbean marine alga Sporochnus bolleanus, has been established as S based on the stereocontrolled synthesis of its (R)-(-)-enantiomer from (S)-epichlorohydrin.