790260-90-1Relevant academic research and scientific papers
Total synthesis of (-)-sporochnol A, the fish deterrent, from a chiral malonate
Fadel, Antoine,Vandromme, Lucie
, p. 1153 - 1162 (2007/10/03)
From a single chiron, the homochiral benzylic malonic acid ester (R)- (+)-2 available with high enantiomeric excess by enzymatic hydrolysis (PLE acetonic powder), enantiomerically pure (-)-sporochnol A 1 was prepared. This versatile method allows preparation of sporochnol 1, via aldehydes 7 and 15, in good overall yield.
An easy access to (S)-pyrrolidinones and -pyrrolidines from chiral benzylic malonates
Arzel, Philippe,Freida, Vincent,Weber, Philippe,Fadel, Antoine
, p. 3877 - 3881 (2007/10/03)
From chiral benzylic malonic acid esters (R)-(+)-4, available with high enantiomeric excesses by enzymatic hydrolysis (PLE acetonic powder), enantiomerically enriched pyrrolidinones 1 and pyrrolidines 2 were prepared. This rapid and competitive method was
Asymmetric Construction of Quaternary Carbons from Chiral Malonates: Selective and Versatile Total Syntheses of the Enantiomers of α- and β-Cuparenones from a Common Optically Active Precursor
Canet, Jean-Louis,Fadel, Antoine,Salauen, Jacques
, p. 3463 - 3473 (2007/10/02)
From a single chiron (R)-4, available with high enantiomeric purity (96percent) by simple enzymatic hydrolysis (PLE) of a prochiral malonate, were prepared convenient precursors of the two enantiomers of α- and β-cuparenones (1a,b and 2a,b).This versatile
