19311-38-7

Basic information

• Product Name: FURAN, 3-CHLOROTETRAHYDRO-
• Synonyms: FURAN, 3-CHLOROTETRAHYDRO-;3-Chlorotetrahydrofuran;3-chlorooxolane
• CAS NO: 19311-38-7
• Molecular Formula: C₄H₇ClO
• Molecular Weight: 106.55
• Mol File: 19311-38-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 151℃
• Flash Point: 54℃
• Appearance: /
• Density: 1.13
• Storage Temp.: Refrigerator, under inert atmosphere
• Solubility: Chloroform (Sparingly), Methanol (Slightly)
• Stability: Volatile
• CAS DataBase Reference: FURAN, 3-CHLOROTETRAHYDRO-(CAS DataBase Reference)
• NIST Chemistry Reference: FURAN, 3-CHLOROTETRAHYDRO-(19311-38-7)
• EPA Substance Registry System: FURAN, 3-CHLOROTETRAHYDRO-(19311-38-7)

Safety Data

• Hazardous Substances Data: 19311-38-7(Hazardous Substances Data)

Usage

Description

3-Chlorotetrahydrofuran, with the molecular formula C4H7ClO, is a colorless liquid classified as a chlorinated cyclic ether. It is a chemical compound that is versatile in its applications across various industries due to its unique properties.

Uses

Used in Chemical Industry:
3-Chlorotetrahydrofuran is used as a solvent in various chemical reactions and industrial processes, facilitating the progress of these reactions and contributing to the efficiency of the processes.
Used in Pharmaceutical Production:
It serves as an intermediate in the production of pharmaceuticals, playing a crucial role in the synthesis of various medicinal compounds, thereby aiding in the development of new drugs and therapies.
Used in Agrochemical Production:
3-Chlorotetrahydrofuran is also utilized as an intermediate in the creation of agrochemicals, which are essential for enhancing crop protection and agricultural productivity.
Used in Organic Compound Synthesis:
FURAN, 3-CHLOROTETRAHYDROis employed in the synthesis of other organic compounds, expanding its utility in the realm of organic chemistry and contributing to the creation of new materials and substances.
Used in Renewable Energy Research:
3-Chlorotetrahydrofuran has been studied for its potential use in the production of renewable biofuels, indicating its possible contribution to sustainable energy solutions and environmental conservation.

Upstream product

• 453-20-3 3-Hydroxytetrahydrofuran 
• 7647-01-0 hydrogenchloride 
• 6117-80-2 1,4-butenediol 
• 3511-19-1 trans-2,3-Dichlorotetrahydrofuran 
• 109-99-9 tetrahydrofuran 
• 821-11-4 1,4-butenediol 
• 3511-19-1 2,3-dichlorotetrahydrofuran 

Downstream Products

• 14631-44-8 3-cyanotetrahydrofuran 
• 627-27-0 homoalylic alcohol 
• 162851-40-3 N-benzyltetrahydrofuran-3-amine 
• 162851-42-5 (Tetrahydro-furan-3-yl)-o-tolyl-amine 
• 162851-44-7 N-tetrahydro[3]furyl-m-toluidine 
• 162851-41-4 N-phenyloxolane-3-amine 
• 162851-46-9 (4-Methoxy-phenyl)-(tetrahydro-furan-3-yl)-amine 
• 162851-43-6 (Tetrahydro-furan-3-yl)-p-tolyl-amine 
• 162851-45-8 (2-Methoxy-phenyl)-(tetrahydro-furan-3-yl)-amine 
• 1708-29-8 2,5-dihydrofuran 

Relevant articles and documents

A 3 - halogenated tetrahydrofuran preparation method

The invention discloses a 3 - halogenated tetrahydrofuran preparation method. The method comprises the following steps: in the organic solvent, 0 - 85 °C temperature, shown in formula I compound with a reducing agent, can be; wherein R1 And R2 The same, they are selected from chlorine or bromine; the reducing agent is sodium borohydride or potassium borohydride; wherein the organic solvent is b [...], 2 - chloroethyl methyl ether, ethyl ether, tetrahydrofuran or methyl tetrahydrofuran. The method of the invention less reaction steps, the process is simple, the product yield can reach 80% - 95%, and the low cost of raw materials, equipment investment, the price of the product there are advantages; in addition the method pollution is small, friendly to the environment, and is suitable for large-scale industrial production.

METHOD FOR PRODUCING 3-AMINOMETHYLTETRAHYDROFURAN DERIVATIVE

An object of the present invention is to provide a process for producing a 3-cyanotetrahydrofuran derivative in a high yield from inexpensive industrial materials. According to the present invention, a 3-aminomethyltetrahydrofuran derivative is produced by preparing a 3-cyanotetrahydrofuran derivative in a high yield from an inexpensive and industrially easily available malic acid derivative, and reducing the cyano group of the 3-cyanotetrahydrofuran derivative.

Introduction of bromine and chlorine substituents in medium ring ethers and lactones

A convenient preparation of α-halo enamines using oxalyl halides is described together with applications of these reagents in the halogenation of β-hydroxy cyclic ethers and lactones.