193902-99-7

Basic information

• Product Name: A90107
• Synonyms: 2-Amino-5-(4-Boc-1-piperazinyl)aniline;A90107
• CAS NO: 193902-99-7
• Molecular Formula: C₁₅H₂₄N₄O₂
• Molecular Weight: 292.381
• Mol File: 193902-99-7.mol
• Article Data: 11

Chemical Properties

• Appearance: /
• CAS DataBase Reference: A90107(CAS DataBase Reference)
• NIST Chemistry Reference: A90107(193902-99-7)
• EPA Substance Registry System: A90107(193902-99-7)

Safety Data

• Hazardous Substances Data: 193902-99-7(Hazardous Substances Data)

Upstream product

• 364-53-4 4-fluoro-1,2-dinitro-benzene 
• 1635-61-6 5-chloro-2-nitroaniline 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 
• 2369-11-1 5-fluoro-2-nitroaniline 
• 1581275-04-8 tert-butyl 4-(4-acetylamino-3-nitrophenyl)piperazine-1-carboxylate 
• 881-50-5 N-(4-bromo-2-nitrophenyl)acetamide 
• 1581275-05-9 tert-butyl 4-(4-amino-3-nitrophenyl)piperazine-1-carboxylate 
• 1046790-71-9 tert-butyl 4-(3,4-dinitrophenyl)piperazine-1-carboxylate 
• 193902-98-6 4-(3-amino-4-nitrophenyl)piperazine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 1581275-12-8 5-(4-(biphenyl-4-ylmethyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1581275-13-9 5-(4-((4'-fluorobiphenyl-4-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1581275-14-0 5-(4-((5-phenylpyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1581275-15-1 5-(4-((5-(4-fluorophenyl)pyridin-3-yl)methyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1581275-16-2 5-(4-(3-(cyclopentenyl)benzyl)piperazin-1-yl)-1H-benzo[d]imidazol-2(3H)-one 
• 1621399-81-2 tert-butyl 4-(2-(2-(tert-butoxycarbonylamino)-4-fluorophenylcarbamoyl)-quinoxalin-6-yl)-piperazine-1-carboxylate 
• 1621399-59-4 C₁₉H₁₉FN₆O 
• 1621399-82-3 tert-butyl 4-(2-(2-amino-5-fluorophenylcarbamoyl)quinoxalin-6-yl)piperazine-1-carboxylate 
• 1621399-60-7 C₁₉H₁₉FN₆O 

Relevant articles and documents

SMALL MOLECULE INHIBITORS OF GALECTIN-3

The present disclosure relates to compounds of Formula (I), which inhibit Gal-3, and include pharmaceutically acceptable salts, compositions comprising such compounds, and methods using and making such compounds and compositions. (Formula (I))

HPK1 INHIBITORS AND METHODS OF USING SAME

Thienopyridinone compounds of Formula (I) and pharmaceutically acceptable salts thereof are described. In these compounds, one of X1; X2, and X3 is S and the other two are each independently CR, wherein R and all other variables are as defined herein. The compounds are shown to inhibit HPK1 kinase activity and to have in vivo antitumor activity. The compounds can be effectively combined with pharmaceutically acceptable carriers and also with other immunomodulatory approaches, such as checkpoint inhibition or inhibitors of tryptophan oxidation. Formula (I).

NOVEL SIGMA-2 RECEPTOR BINDERS AND THEIR METHOD OF USE

Pharmaceutical compositions of the invention comprise functionalized lactone derivatives having a disease-modifying action in the treatment of diseases associated with dysregulation of sigma-2 receptor activity.