19449-26-4

Usage

Uses

Used in Organic Synthesis:
2-Dimethylamino-1,3-dioxolane is used as a reagent in organic synthesis for its ability to facilitate selective reactions without interference from the alcohol functional group.
Used as a Protecting Group for Alcohols:
In the field of organic chemistry, 2-Dimethylamino-1,3-dioxolane serves as a protecting group for alcohols, enabling chemists to carry out specific reactions while preventing unwanted side reactions involving the alcohol group.
Used as a Solvent:
Due to its properties, 2-Dimethylamino-1,3-dioxolane can be employed as a solvent in various chemical processes, aiding in the dissolution and interaction of different compounds.
Used in Pharmaceutical Synthesis:
2-Dimethylamino-1,3-dioxolane is utilized as a precursor in the synthesis of pharmaceuticals, contributing to the development of new drugs and medicinal compounds.
Used in Industrial Chemistry:
Its versatility and properties make 2-Dimethylamino-1,3-dioxolane a valuable component in industrial chemistry, where it can be applied across different sectors for the production of a wide range of organic compounds.

InChI:InChI=1/C5H11NO2/c1-6(2)5-7-3-4-8-5/h5H,3-4H2,1-2H3

Upstream product

• 107-21-1 ethylene glycol 
• 1188-33-6 N,N-dimethylformamide diethyl diacetal 
• 3646-10-4 1,4,6,9-tetraoxa-5λ₅-phosphaspiro[4,4]nonane 
• 4637-24-5 N,N-dimethyl-formamide dimethyl acetal 
• 1073-75-2 2-(2'-hydroxyethoxy)-1,3,2-dioxaphospholane 

Downstream Products

• 4746-97-8 cyclohexanedione monoethylene ketal 
• 183-97-1 1,4,9,12-Tetraoxa-dispiro[4.2.4.2]tetradecane 
• 687-48-9 ethyl N,N-dimethylcarbamate 
• 107-21-1 ethylene glycol 
• 68-12-2 N,N-dimethyl-formamide 
• 96-49-1 [1,3]-dioxolan-2-one 
• 140-08-9 tris(2-chloro-ethyl)phosphite 

Relevant academic research and scientific papers

N-Alkylation of 4-Chloro-5-cyano-1,2,3-triazole with Orthoformic Acid Derivatives

The N-alkylation of 4-chloro-5-cyano-1,2,3-triazole with methyl and ethyl orthoformate, and the dimethyl, diethyl and ethylene acetals of DMF has been examined.Methylation gives all three N-methyl isomers, whereas ethylation and hydroxyethylation gives 2-N-alkyl derivatives only.It has been shown for the first time that it is possible to use DMF ethylene acetal to obtain N-hydroxyethylazoles.The structure of the products were established by 13C NMR spectroscopy.

Synthesis of the new types of N-substituted aminomethylenebisorganophosphorus acids and their derivatives

The interaction of esters of trivalent organophosphorus acids containing PH and POSiMe3 fragments with various derivatives of formamide is proposed as convenient methods for the synthesis of new N-substituted aminomethylenebisorganophos-phorus acids and their derivatives with three-, four-, and five-coordinated phosphorus. Also the new functionalized derivatives of the new aminomethylenebisphosphinic acids with substituted hydroxymethyl moieties are synthesized, and some properties of the obtained compounds are presented.

NEW TYPES OF AMINOMETHYL ORGANOPHOSPHORUS COMPOUNDS

We studied aminomethylation of various PH acids their derivatives containing highly reactive PH, PSi, POSi and PC(O) fragments: tris(trimethylsilyl)phosphine, trimethylsilyl esters of phosphorus(III) acids, pivaloylphosphonite, and hydrospirophosphoranes.Chloro-, alkoxy- or dialkylaminomethylamines, dialkylformamide acetals, azomethines, and enamines were used as aminomethylating reagents.Convenient methods for synthesizing previously unknown or difficult-to-obtain organic compounds of two-, three-, four, and five-coordinate phosphorus containing a P-C-N fragment were proposed.