195073-71-3

Upstream product

• 4235-20-5 5-chloro-2-phenylsulfanyl-aniline 
• 75-36-5 acetyl chloride 
• 108-98-5 thiophenol 
• 4548-56-5 4-chloro-2-nitrophenyl phenyl sulfide 

Downstream Products

• 195073-75-7 N-[2-(4-Acetyl-phenylsulfanyl)-5-chloro-phenyl]-3-bromo-propionamide 
• 195073-76-8 3-Bromo-N-{5-chloro-2-[4-(2-methyl-[1,3]dioxolan-2-yl)-phenylsulfanyl]-phenyl}-propionamide 
• 195073-80-4 N-(3-bromopropyl)-5-chloro-2-(4-acetoxythiophenyl)phenylamine 

Relevant academic research and scientific papers

New spermine and spermidine derivatives as potent inhibitors of trypanosoma cruzi trypanothione reductase

Several spermine and spermidine derivatives containing 2-amino diphenylsulfide substituents were prepared and tested for their inhibiting effects on Trypanosoma cruzi trypanothione reductase. IC50 values were assessed between 0.3 and 3 μM. Compound 32 (K(i) = 0.4 μM) is the most potent TR inhibitor described so far.