A novel immunostimulator, N2-[α-O-Benzyl-N-(acetylmuramyl) -L-alanyl-D-isoglutaminyl]-N6-trans-(m-nitrocinnamoyl)-L-lysine, and its adjuvancy on the hepatitis B surface antigen

DOI: 10.1021/jm0493313

Source and publish data:

Journal of Medicinal Chemistry p. 5112 - 5122 (2005)

Update date:2022-08-10

Topics:

Authors:

Yang, Hong-Zhen

Xu, Song

Liao, Xue-Yan

Zhang, Suo-De

Liang, Zheng-Lun

Liu, Bai-He

Bai, Jin-Ye

Jiang, Chao

Ding, Jian

Cheng, Gui-Fang

Liu, Gang

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Article abstract of DOI:10.1021/jm0493313

N²-[α-O-Benzyl-N-(acetylmuramyl)-L-alanyl-D-isoglutaminyl] -N⁶-trans-(m-nitrocinnamoyl)-L-lysine (muramyl dipeptide C, or MDP-C) has been synthesized as a novel, nonspecific immunomodulator. The present study shows that MDP-C induces

Full text of DOI:10.1021/jm0493313

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