196505-06-3

Upstream product

• 196504-90-2 5-amino-1-benzyl-3-phenyl-1H-pyrazole-4-carbonitrile 
• 20570-96-1 benzylhydrazine dihydrochloride 
• 13846-64-5 2-Cyano-3-methylthio-3-phenylacrylonitrile 
• 2168-78-7 methyl dithiobenzoate 
• 196505-04-1 1-Benzyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-ol 

Downstream Products

• 196505-09-6 (1-Benzyl-3-phenyl-1H-pyrazolo[3,4-d]pyrimidin-4-yl)-(3-chloro-phenyl)-amine 

Relevant academic research and scientific papers

Use of a pharmacophore model for the design of EGF-R tyrosine kinase inhibitors: 4-(Phenylamino)pyrazolo[3,4-d]pyrimidines

In the course of the random screening of a pool of CIBA chemicals, the two pyrazolopyrimidines 1 and 2 have been identified as fairly potent inhibitors of the EGF-R tyrosine kinase. Using a pharmacophore model for ATP- competitive inhibitors interacting w