197145-37-2

Basic information

• Product Name: 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone
• Synonyms: 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone;3-(DIMETHYLAMINO)-1-(3-METHOXYPHENOL)-2-METHOXYPROPAN-1-ONE HYDROCHLORIDE;3-(diMethylaMino)-1-(3-Methoxyphenyl)-2-Methylpropan-1-one;1-Propanone,3-(diMethylaMino)-1-(3-Methoxyphenyl)-2-Methyl-;-2-methylpropan-1-one;3-(dimethylamino)-l -(3-methoxyphenyl)-2-methyl-l -propanone
• CAS NO: 197145-37-2
• Molecular Formula: C₁₃H₁₉NO₂
• Molecular Weight: 221.29546
• Mol File: 197145-37-2.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 315.8 °C at 760 mmHg
• Flash Point: 144.8 °C
• Appearance: /
• Density: 1.012 g/cm³
• Vapor Pressure: 0.000428mmHg at 25°C
• Refractive Index: 1.508
• CAS DataBase Reference: 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone(197145-37-2)
• EPA Substance Registry System: 3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone(197145-37-2)

Safety Data

• Hazardous Substances Data: 197145-37-2(Hazardous Substances Data)

Usage

General Description

3-(Dimethylamino)-1-(3-methoxyphenyl)-2-methyl-1-propanone is a complex organic compound with potential applications in chemical research and industrial sectors. The molecule is characterised by an interesting mix of functional groups including a dimethylamino group, a methoxyphenyl group and a propanone functionality, which makes it an intriguing subject for chemical alteration and reaction. Its structure suggests it may demonstrate interesting physical and chemical properties, possibly including unique reactivity profiles, polarity, solubility behaviours, and electronic configurations. Further research and experimentation are required to fully understand the particular characteristics and potential uses of this chemical compound.

InChI:InChI=1/C13H19NO2/c1-10(9-14(2)3)13(15)11-6-5-7-12(8-11)16-4/h5-8,10H,9H2,1-4H3

Upstream product

• 37951-49-8 1-(3-methoxyphenyl)propan-1-one 
• 51-80-9 bis-(dimethylamino)methane 
• 3027-13-2 1-(3-methoxyphenyl)propan-2-one 
• 50-00-0 formaldehyd 
• 506-59-2 N,N-dimethylammonium chloride 
• 37951-53-4 3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one hydrochloride 

Downstream Products

• 1217854-15-3 (R)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one 
• 850222-41-2 (S)-3-(dimethylamino)-1-(3-methoxyphenyl)-2-methylpropan-1-one (2R,3R)-O,O'-dibenzoyltartrate 
• 175590-76-8 (2RS,3RS)-1-dimethylamino-3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol 
• 809282-29-9 3-(3-methoxyphenyl)-N,N,2-trimethylpent-3-en-1-amine 
• 1314003-30-9 (R,R)-tapentadol-PABA carbamate trifluoroacetate 
• 1314003-88-7 (R,R)-tapentadol-(PABA tert-butyl ester) carbamate 
• 850222-40-1 (2S)-3-dimethylamino-1-(3-methoxyphenyl)-2-methyl-1-propanone 
• 175590-76-8 (2SS,3RS)-[3-(3-methoxy-phenyl)-2-methyl-pentan-3-ol]-dimethylamine 
• 175591-22-7 (βR,γR)-γ-ethyl-N,N,β-trimethyl-3-methoxybenzenepropanamine 
• 175591-23-8 tapentadol 
• 175591-09-0 tapentadol hydrochloride 
• 213257-55-7 (2RS)-3-dimethylamino-1,1-bis-(3-methoxy-phenyl)-2-methyl-propan-1-ol hydrochloride 

Relevant articles and documents

A NOVEL PROCESS FOR THE PREPARATION OF 1-PHENYL-3-AMINOPROPANE DERIVATIVES

The present invention relates to a novel process for the preparation of 1-phenyl-3- aminopropane derivative compounds corresponding to the formula (I) and/or its intermediates, and/or its stereo specific isomers or pharmaceutically acceptable salts, hydra

AMINO ACID AND PEPTIDE CARBAMATE PRODRUGS OF TAPENTADOL AND USES THEREOF

Prodrugs of tapentadol with amino acids or short peptides, pharmaceutical compositions containing such prodrugs and a method for providing pain relief with the tapentadol prodrugs are provided herein. Prodrugs having side chains of valine, leucine, isoleucine and glycine amino acids and mono-, di- and tripeptides thereof are preferred. Additionally, methods for avoiding or minimizing the adverse gastrointestinal side effects associated with tapentadol administration, as well as increasing the oral bioavailability of tapentadol are provided herein.

PROCESS FOR THE PREPARATION OF (1R,2R)-3-(3-DIMETHYLAMINO-1-ETHYL-2-METHYL-PROPYL)-PHENOL

The present invention relates to a process for the preparation of (1 R,2R)-3- dimethylamino-1-ethyl-2-methyl-propyl)-phenol.