19715-32-3Relevant academic research and scientific papers
PYRROLO SULFONAMIDE COMPOUNDS FOR MODULATION OF ORPHAN NUCLEAR RECEPTOR RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORGAMMA, NR1F3) ACTIVITY AND FOR THE TREATMENT OF CHRONIC INFLAMMATORY AND AUTOIMMUNE DISEASES
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, (2012/11/06)
The invention provides modulators for the orphan nuclear receptor RORy and methods for treating RORy mediated diseases by administrating these novel RORy modulators to a human or a mammal in need thereof. Specifically, the present invention provides pyrrolo sulfonamide compounds of Formula (1) and the enantiomers, diastereomers, tautomers, solvates and pharmaceutically acceptable salts thereof.
The electronic effects of bulky aryl substituents on low coordinated phosphorus atoms in diphosphenes and phosphaalkenes by functionalization at the para position
Kawasaki, Subaru,Nakamura, Akitake,Toyota, Kozo,Yoshifuji, Masaaki
, p. 1110 - 1120 (2007/10/03)
The electronic effects of bulky aryl substituents on low coordinated phosphorus atom(s) in diphosphenes and phosphaalkenes have been examined by means of functionalization at the para position of the substituents. Bulky bromobenzenes bearing an electron-d
Preparation and properties of sterically protected diphosphene and fluorenylidenephosphine bearing the 2,6-di-tert-butyl-4-methoxyphenyl group
Toyota, Kozo,Kawasaki, Subaru,Nakamura, Akitake,Yoshifuji, Masaaki
, p. 430 - 431 (2007/10/03)
A new bulky bromobenzene, 2-bromo-1,3-di-tert-butyl-5-methoxybenzene, was prepared and utilized to preparations of the corresponding diphosphene and fluorenylidenephosphine including low-coordinate phosphorus atom(s). An electronic perturbation of the p-m
SOME NEW PROTECTIVE GROUPS FOR STABILIZING LOW COORDINATED PHOSPHORUS COMPOUNDS
Yoshifuji, Masaaki,Sasaki, Shigeru,Shiomi, Daisuke,Niitsu, Takashi,Inamoto, Naoki
, p. 325 - 328 (2007/10/02)
Sterically stabilized diphosphenes and 1,3-diphosphaallenes by 2,4-di-t-butylphenyl or 2,4,6-tri-t-pentylphenyl groups were prepared.
A VERSATILE PREPARATION OF 2,6-DI-t-BUTYLBROMOBENZENE. APPLICATION TO STERIC PROTECTION FOR ORGANOPHOSPHORUS COMPOUNDS IN LOW COORDINATION STATES
Yoshifuji, Masaaki,Niitsu, Takashi,Shiomi, Daisuke,Inamoto, Naoki
, p. 5433 - 5436 (2007/10/02)
2,6-di-t-butylbromobenzene (5) was prepared from 2,4,6-tri-t-butyl-bromobenzene by ipso nitration followed by reduction of the nitro group and deamination.The diphosphene (8) and 1,3-diphosphaallene (10) were prepared.
