19728-41-7

Usage

Uses

Used in Proteomics Research:
2-TERT-BUTYLTHIOPHENOL serves as a specialty product in proteomics research, where it aids in the study of proteins and their interactions within biological systems. Its unique chemical structure allows it to be used as a valuable tool for analyzing and identifying proteins, contributing to a better understanding of their functions and roles in various biological processes.
Used in Organic Synthesis:
In the field of organic synthesis, 2-TERT-BUTYLTHIOPHENOL acts as an intermediate, playing a crucial role in the formation of more complex organic molecules. Its reactivity and structural features make it a versatile building block for synthesizing a wide range of compounds, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
2-TERT-BUTYLTHIOPHENOL is also utilized as an intermediate in the development and production of pharmaceuticals. Its unique properties and reactivity enable the creation of new drug candidates and the improvement of existing medications, ultimately contributing to advancements in healthcare and the treatment of various diseases and conditions.

InChI:InChI=1/C10H14S/c1-10(2,3)8-6-4-5-7-9(8)11/h4-7,11H,1-3H3

Upstream product

• 6310-21-0 2-(1,1-dimethylethyl)-benzenamine 
• 16241-15-9 S-(2-tert-butylphenyl)dimethylthiocarbamate 
• 19862-70-5 2-tert-butylphenyl disulfide 
• 88-18-6 2-tert-Butylphenol 
• 3282-56-2 4-tert-butylnitrobenzene 
• 16241-14-8 O-(2-(tert-butyl)phenyl) N,N-dimethylcarbamothioate 
• 16420-13-6 N,N-Dimethylthiocarbamoyl chloride 
• 6310-17-4 2-bromo-1-tert-butyl-4-nitrobenzene 
• 7073-99-6 2-tert-butylbromobenzene 

Downstream Products

• 63818-32-6 Benzyl-o-tert.-butylphenylsulfon 
• 198123-71-6 Toluene-4-thiosulfonic acid S-(2-tert-butyl-phenyl) ester 
• 913961-18-9 4-(2-tert-butyl-benzenesulfanyl)-nitrobenzene 
• 63818-31-5 methyl o-t-butylphenyl sulphone 
• 177365-41-2 2-bromo-6-tert-butylthiophenol 
• 912332-73-1 1-tert-butyl-2-(2-chloro-allylsulfanyl)-benzene 
• 321733-36-2 [(Au(SC₆H₄C(CH₃)3))6] 
• 1202637-99-7 tert-butylphenyl thioether 
• 1308834-14-1 2-[(2-tert-butylphenyl)sulfanyl]ethyl phenyl sulfone 
• 1308833-74-0 2-[(2-tert-butylphenyl)sulfinyl]ethyl phenyl sulfone 
• 1308834-34-5 (S)-2-tert-butylphenyl methyl sulfoxide 
• 1308833-94-4 (R)-2-tert-butylphenyl methyl sulfoxide 
• 1297473-51-8 C₂₅H₃₁N₃O₂S₃ 
• 19862-70-5 2-tert-butylphenyl disulfide 

Relevant academic research and scientific papers

Method of preparation of organosilyl substituted aromatic or heteroaromatic compounds

An improved method of preparing an ortho-, meta- or para-silyl aromatic or heteroaromatic compound represented by the formula STR1 wherein X is oxygen or sulfur, R1 represents the atoms necessary to complete an unsubstituted or substituted arom

Rapid and Selective Reduction of Functionalized Aromatic Disulfides with Lithium Tri-tert-butoxyaluminohydride. A Remarkable Steric and Electronic Control. Comparison of Various Hydride Reagents

Lithium tri-tert-butoxyaluminohydride (LTBA), an exceptionally mild reducing agent in organic synthesis, reduces functionalized aromatic disulfides to the corresponding thiols in quantitative yield.The reaction is rapid (for example, o-tolyl disulfide is reduced to completion in 60 min at 25 deg C) and can tolerate a wide variety of functional groups, such as halogen, nitro, carboxylic acid, and their derivatives.The presence of electron-withdrawing substituents dramatically enhances the rate of reduction (p-chlorophenyl disulfide is quantitatively reduced in 30 s) and electron-releasing substituents diminishes the rate of cleavage.The reaction is sensitive to steric effects (2,4-di-tert-pentylphenyl disulfide underwent 25percent reduction in 24 h).However, such hindered disulfides can be rapidly and quantitatively reduced in refluxing THF.The reaction of LTBA with alkyl disulfides is extremely sluggish.The reaction provides a useful and simple means for the facile and selective reduction of aromatic disulfides where this is required in synthetic operations.