197850-97-8

Basic information

• Product Name: Butanoic acid, 4,4,4-trifluoro-3,3-dihydroxy-, ethyl ester
• CAS NO: 197850-97-8
• Molecular Formula: C6H9F3O4
• Molecular Weight: 202.13
• Mol File: 197850-97-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Butanoic acid, 4,4,4-trifluoro-3,3-dihydroxy-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Butanoic acid, 4,4,4-trifluoro-3,3-dihydroxy-, ethyl ester(197850-97-8)
• EPA Substance Registry System: Butanoic acid, 4,4,4-trifluoro-3,3-dihydroxy-, ethyl ester(197850-97-8)

Safety Data

• Hazardous Substances Data: 197850-97-8(Hazardous Substances Data)

Upstream product

• 106260-08-6 ethyl 3-trifluoromethyl-3-oxo-propionate 
• 383-63-1 ethyl trifluoroacetate, 
• 141-78-6 ethyl acetate 

Downstream Products

• 106260-08-6 ethyl 3-trifluoromethyl-3-oxo-propionate 
• 372-31-6 ethyl 4,4,4-trifluoroacetoacetate 

Relevant articles and documents

Candida Rugosa lipase-catalyzed kinetic resolution of β-hydroxy- β-arylpropionates and δ-hydroxy-δ-aryl-β-oxo-pentanoates

A simple and convenient method was reported for the preparation of optically active β-hydroxy-β-arylpropionates, δ-hydroxy-δ- aryl-β-oxo-pentanoates and their butyryl derivatives via CRL-catalyzed hydrolysis. The optically active products are potential precursors of some chiral pharmaceuticals and natural products.

Regioselectivity in the Ring Opening of 2-Alkylcyclopropylmethyl Radicals: the Effect of Electronegative Substituents

The regioselectivity of the ring-opening of the trans-2-alkylcyclopropylmethyl radical A to give the primary alkyl radicals B, or the secondary alkyl radicals C, has been investigated, where the groups R and/or CXY carry electronegative substituents.All these reactions gave principally the secondary alkyl radicals C, whereas, in the absence of electronegative substituents, ring-opening occurs in favour of the primary alkyl radicals B.This regioselectivity is interpreted in terms of the frontier orbital interactions which are involved.