3598-14-9

Basic information

• Product Name: PHENOXYACETONITRILE
• Synonyms: 2-PHENOXYACETONITRILE;PHENOXYACETONITRILE;Phenoxyacetonirile;Phenoxyacetonitrile,98%;Phenoxymethyl cyanide;Phenoxyacetonitrile 98%
• CAS NO: 3598-14-9
• Molecular Formula: C₈H₇NO
• Molecular Weight: 133.15
• Product Categories: Aromatic Nitriles;C8 to C9;Cyanides/Nitriles;Nitrogen Compounds
• Mol File: 3598-14-9.mol
• Article Data: 24

Chemical Properties

• Boiling Point: 235-238 °C(lit.)
• Flash Point: >230 °F
• Appearance: clear light yellow-brown liquid
• Density: 1.09 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0381mmHg at 25°C
• Refractive Index: n20/D 1.524(lit.)
• Storage Temp.: 2-8°C
• BRN: 2206192
• CAS DataBase Reference: PHENOXYACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENOXYACETONITRILE(3598-14-9)
• EPA Substance Registry System: PHENOXYACETONITRILE(3598-14-9)

Safety Data

• Hazard Codes: Xn
• Statements: 20/21/22
• Safety Statements: 36
• RIDADR: 3276
• WGK Germany: 3
• HazardClass: 6.1
• PackingGroup: III
• Hazardous Substances Data: 3598-14-9(Hazardous Substances Data)

Usage

Chemical Properties

clear light yellow-brown liquid

Uses

Different sources of media describe the Uses of 3598-14-9 differently. You can refer to the following data:
1. Phenoxyacetonitrile is a building block that has been used as a reactant for the preparation of [[(oxo)pyridazinyl]phenoxy]acetonitrile derivatives to be used as vasodilators.
2. Phenoxyacetonitrile may be used in the synthesis of:2,4-dihydroxyphenoxyacetophenonesmethylthio(phenoxy)acetonitrile2,4-diamino-5-(3,4,5-trimethoxyphenoxy)pyrimidine

InChI:InChI=1/C8H7NO/c9-6-7-10-8-4-2-1-3-5-8/h1-5H,7H2

Upstream product

• 107-14-2 chloroacetonitrile 
• 108-95-2 phenol 
• 13610-02-1 1-phenoxy-2-propyne 
• 590-17-0 cyanomethyl bromide 
• 98-80-6 phenylboronic acid 
• 19158-51-1 P-toluenesulfonyl cyanide 
• 100-66-3 methoxybenzene 
• 172876-96-9 3-oxo-1λ³-benzo[d][1,2]iodaoxole-1(3H)-carbonitrile 
• 75-05-8 acetonitrile 
• 1758-46-9 2-phenoxyethanamine 
• 3229-70-7 phenolate 
• 2120-70-9 2-phenoxyethanal 
• 139-02-6 sodium phenoxide 
• 32438-31-6 (2,2-diethoxy-ethoxy)-benzene 

Downstream Products

• 851443-13-5 1-phenoxy-hexan-2-one 
• 35855-76-6 1-phenoxy-3-phenylpropan-2-one 
• 73014-19-4 1-(2,4-dihydroxyphenyl)-2-phenoxyethan-1-one 
• 741222-44-6 2-Phenoxy-acetimidic acid methyl ester 
• 136346-92-4 (Z)-5-Amino-2,2-dimethyl-6-phenoxy-hex-4-en-3-one 
• 105199-28-8 (6-Nitro-5-quinolinyl)acetonitrile 
• 708-58-7 2-(4-fluoro-2-nitrophenyl)acetonitrile 
• 105003-93-8 2-fluoro-6-nitrobenzeneacetonitrile 
• 119657-10-2 (2-benzoyl-4-nitrophenyl)acetonitrile 
• 119657-11-3 (4-benzoyl-2-nitrophenyl)acetonitrile 
• 119657-13-5 3-hydroxy-3-(3-nitrophenyl)-3-phenyl-2-phenoxy-propionitrile 
• 89277-98-5 2-(2-chloro-6-nitrophenyl)acetonitrile 
• 87081-90-1 (4-chloro-2-nitro-phenyl)-acetonitrile 
• 119679-96-8 (5-benzoyl-2-nitrophenyl)(phenoxy)acetonitrile 

Relevant articles and documents

Direct C(sp3)-H Cyanation Enabled by a Highly Active Decatungstate Photocatalyst

A highly efficient, direct C(sp3)-H cyanation was developed under mild photocatalytic conditions. The method enabled the direct cyanation of various C(sp3)-H substrates with excellent functional group tolerance. Notably, complex natural products and bioactive compounds were efficiently cyanated.

A metal-free direct C (sp3)-H cyanation reaction with cyanobenziodoxolones

A metal-free protocol of direct C(sp3)-H cyanation with cyanobenziodoxolones functioning as both cyanating reagents and oxidants was developed. Unactivated substrates, such as alkanes, ethers and tertiary amines, were thereby transformed to the corresponding nitriles in moderate to high yields. Mechanistic studies indicated that the cyanation proceeded with two potential pathways, which is highly dependent on the substrates: (1) a free radical case for alkanes and ethers and (2) an oxidative case for tertiary amines.

IODONIUM SALT COMPOUND, PHOTOACID GENERATOR AND COMPOSITION CONTAINING THE SAME, AND METHOD FOR MANUFACTURING DEVICE

PROBLEM TO BE SOLVED: To provide an iodonium salt compound which can be used as a chemical amplification type photoacid generator for resist and a photocationic polymerization initiator, has high sensitivity to an i-line at a wavelength of 365 nm, and has high solubility to an organic solvent and a resin. SOLUTION: A new iodonium salt compound is represented by the following iodonium salts 2, 5 and 10. SELECTED DRAWING: Figure 1 COPYRIGHT: (C)2019,JPOandINPIT