Synthesis of 7,8-dimethoxy-2-oxo-1,3,4,5-tetrahydropyrrolo[4,3,2-de]quinoline: A key intermediate en route to makaluvamines, discorhabdin C and other marine alkaloids of this group via vicarious nucleophilic substitution of hydrogen

Article abstract of DOI:10.1055/s-1997-1325

The title compound 1a, a key intermediate in synthesis of an important group of alkaloids, is efficiently prepared via vicarious nucleophilic substitution of hydrogen followed by simple transformations.