1984-58-3

Usage

Chemical Properties

clear colorless to very slightly yellow liquid

InChI:InChI=1/C7H6Cl2O/c1-10-7-4-5(8)2-3-6(7)9/h2-4H,1H3

Upstream product

• 1435-50-3 2-bromo-1,4-dichlorobenzene 
• 124-41-4 sodium methylate 
• 348-59-4 1,4-dichloro-2-fluorobenzene 
• 583-78-8 2,5-dichlorophenol 
• 77-78-1 dimethyl sulfate 
• 67-56-1 methanol 
• 120-82-1 1,2,4-Trichlorobenzene 
• 74-88-4 methyl iodide 
• 29682-41-5 2,5-dichloroiodobenzene 

Downstream Products

• 583-78-8 2,5-dichlorophenol 
• 7051-13-0 1-chloro-2,4-dimethoxybenzene 
• 13726-14-2 4-chloro-m-anisidine 
• 73239-06-2 2,5-dichloro-4-methoxyacetophenone 
• 72482-69-0 2,5-dichloro-4-(2-fluorobenzoyl)anisole 
• 1429342-60-8 1,4-bis(4-pyridyl)-2-methoxybenzene 
• 1445983-56-1 5-(2,5-dichloro-4-(((R)-4-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)thiazolidin-3-yl)methyl)phenyl)-N-((2S,3R,4R,5R)-2,3,4,5,6-pentahydroxyhexyl)pentanamide 
• 1445985-74-9 (R)-2,5-dichloro-4-((4-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)thiazolidin-3-yl)methyl)phenyl trifluoromethanesulfonate 
• 1445983-29-8 (R)-5-(2,5-dichloro-4-((4-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)thiazolidin-3-yl)methyl)phenyl)pentanoic acid 
• 1445985-59-0 (R)-methyl 5-(2,5-dichloro-4-((4-(4-cyclopropyl-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)thiazolidin-3-yl)methyl)phenyl)pentanoate 
• 1445985-58-9 methyl 5-(4-(bromomethyl)-2,5-dichlorophenyl)pentanoate 
• 1445985-57-8 methyl 5-(2,5-dichloro-4-(hydroxymethyl)phenyl)pentanoate 
• 1445985-56-7 methyl 5-(2,5-dichloro-4-formylphenyl)pentanoate 
• 1445985-55-6 methyl 5-(2,5-dichloro-4-formylphenyl)pent-4-ynoate 

Relevant academic research and scientific papers

Electrochemical methoxylation of alkenyldichloroanisoles

Electrochemical oxidation of chlorinated alkenylanisoles in anhydrous methanol was studied. Pleiades Publishing, Inc., 2006.

Synthesis of bis[(3,4-ethylenedioxy)thien-2-yl]-substituted benzenes

A series of bis-EDOT-aryl monomers have been synthesized, which have blue emission characteristics with quantum yields ranging from 0.01% to 10.3%. Polymers were obtained by electrochemical synthesis. Cyclic voltammetry was employed to characterize the electrochemical behavior of these systems.

Active Molybdenum-Based Anode for Dehydrogenative Coupling Reactions

A new and powerful active anode system that can be operated in 1,1,1,3,3,3-hexafluoro-2-propanol (HFIP) has been discovered. In HFIP the molybdenum anode forms a compact, conductive, and electroactive layer of higher-valent molybdenum species. This system can replace powerful but stoichiometrically required MoV reagents for the dehydrogenative coupling of aryls. This electrolytic reaction is more sustainable and allows the conversion of a broad scope of activated arenes.

SELECTIVE HYDROLYSIS AND ALCOHOLYSIS OF CHLORINATED BENZENES

The present invention relates to a process for providing a compound of formula (I):, wherein R is hydrogen or R', wherein R' is –(C1-C4)alkyl, and Hal is a halogen, the process comprising the step of: reacting a compound of formula (II) wherein Hal is defined as above, with an alkali metal alkoxide of the formula XOR', wherein X is an alkali metal, and R' is defined as above.

PROCESS FOR HYDROLYZING 1,2,4-TRIHALOBENZENE

The present invention relates to a process for providing a compound of formula (I): wherein Hal is a halogen, the process comprising the step of: reacting a compound of formula (II) wherein Hal is defined as above, with an alkali metal sulfite of the formula X2SO3 and an alkali metal hydroxide of the formula YOH, wherein X and Y are independently selected from an alkali metal.

1,2-benzisoxazoloxyacetic acids and related compounds

Novel 1,2-benzisoxazoloxyacetic acids and related compounds, methods for preparing same and methods of treatment by administering compositions containing such a compound are described. These compounds are useful as diuretic, uricosuric and antihypertensive agents.

THE REACTIONS OF UNACTIVATED ARYL HALIDES WITH SODIUM METHOXIDE IN HMPA; SYNTHESIS OF PHENOLS, ANISOLES, AND METHOXYPHENOLS

Sodium methoxide reacts with dichlorobenzenes in HMPA to give the chloroanisoles as a result of a SNAr process.Excess MeONa then effects the demethylation of the ethers to give the chlorophenols via an SN2 reaction.With tri- and tetrachlorobenzenes the initially formed chloroanisoles can be dealkylated to chlorophenols or can suffer further substitution to give the chlorodimethoxybenzenes; these react with excess MeONa to give the chloromethoxyphenols.The results obtained with the various isomers of the di-, tri-, and tetrachlorobenzenes are presented and discussed on the basis of the electronic effects of the substituents.