19879-30-2

Basic information

• Product Name: BAVACHININ A
• Synonyms: BAVACHININ A;4'-HYDROXY-7-METHOXY-6-(3-METHYL-2-BUTENYL)-FLAVANONE;(s)-butenyl);2,3-dihydro-2-(4-hydroxyphenyl)-7-methoxy-6-(3-methyl-2-4h-1-benzopyran-4-on;4’-hydroxy-7-methoxy-6-(3-methyl-2-butenyl)-flavanon;7-o-methylbavachin;bavachinin;BAVACHININ A(P)
• CAS NO: 19879-30-2
• Molecular Formula: C21H22O4
• Molecular Weight: 338.4
• Product Categories: Flavanones
• Mol File: 19879-30-2.mol
• Article Data: 5

Chemical Properties

• Melting Point: 139-145°C
• Boiling Point: 537.1 °C at 760 mmHg
• Flash Point: 190.3 °C
• Appearance: /
• Density: 1.182
• Vapor Pressure: 3.76E-12mmHg at 25°C
• Refractive Index: 1.589
• Storage Temp.: ?20°C
• PKA: 9.66±0.30(Predicted)
• CAS DataBase Reference: BAVACHININ A(CAS DataBase Reference)
• NIST Chemistry Reference: BAVACHININ A(19879-30-2)
• EPA Substance Registry System: BAVACHININ A(19879-30-2)

Safety Data

• Hazard Codes: N
• Statements: 50
• Safety Statements: 61
• RIDADR: UN 3077 9 / PGIII
• WGK Germany: 3
• Hazardous Substances Data: 19879-30-2(Hazardous Substances Data)

Usage

Uses

Bavachinin is a natural component of Psoralea corylifolia which has been shown to improve insulin-dependant glucose uptake through insuling signaling AMPK activation. Also used as peroxisome proliferator activated receptor γ agonists in the treatment of diabetes.

InChI:InChI=1/C21H22O4/c1-13(2)4-5-15-10-17-18(23)11-20(14-6-8-16(22)9-7-14)25-21(17)12-19(15)24-3/h4,6-10,12,20,22H,5,11H2,1-3H3

Upstream product

• 129097-15-0 2-(4-hydroxyphenyl)-7-methoxy-6-(3-methylbut-2-en-1-yl)chroman-4-one 
• 28448-83-1 2′-hydroxyl-4′-methoxyl-5′-isopentenylacetophenone 
• 128961-25-1 1-(4-methoxy-2-((3-methylbut-2-en-1-yl)oxy)phenyl)ethan-1-one 
• 123-08-0 4-hydroxy-benzaldehyde 
• 552-41-0 1-(2-hydroxy-4-methoxyphenyl)ethanone 
• 6515-21-5 4-methoxymethoxy-benzaldehyde 
• 128961-19-3 7-methoxy-2-(4-(methoxymethoxy)phenyl)-6-(3-methylbut-2-en-1-yl)chroman-4-one 
• 20784-60-5 (E)-1-(2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-hydroxyphenyl)prop-2-en-1-one 
• 128961-13-7 (E)-1-(2-hydroxy-4-methoxy-5-(3-methylbut-2-en-1-yl)phenyl)-3-(4-(methoxymethoxy)phenyl)prop-2-en-1-one 

Relevant articles and documents

2-phenylchroman-4-one derivatives and antiviral composition comprising the same

The present invention relates to a 2-phenylchroman-4-one derivative or a pharmaceutically acceptable salt thereof, a method for manufacturing the same, and a therapeutic agent for MERS containing the same as an active component. A compound containing the

Separation and peroxisome proliferator-activated receptor-γ agonist activity evaluation of synthetic racemic bavachinin enantiomers

Abstract Bavachinin, isolated from Psoralea corylifolia seeds, has been reported to demonstrate peroxisome proliferator-activated receptor-γ (PPAR-γ) agonist activity. However, isolated bavachinin is actually a mixture of S and R configurations, with an e

An Improved Procedure for Cyclisation of Chalcones to Flavanones Using Celite Supported Potassium Fluoride in Methanol: Total Synthesis of Bavachinin

Chalcones may be cyclised to the corresponding flavanones by stirring with KF - celite suspended in methanol at reflux.This method gives consistently higher conversion than other reported procedures and its utility is illustrated by the synthesis of the l