199010-68-9Relevant academic research and scientific papers
1-[2'-(trimethylsilyl)ethoxymethyl]-2-phenylsulfonylimidazole: A new reagent for the preparation of C-4 substituted imidazoles
Phillips, James G.,Fadnis, Leena,Williams, David R.
, p. 7835 - 7838 (2007/10/03)
The title compound provides for the efficient C-4 metallation of the imidazole nucleus. Further reactions lead to trisubstituted imidazoles which can be selectively deprotected at the N1 and C2 positions under mild conditions to maximize the potential for further elaboration.
