201225-43-6

Upstream product

• 136923-03-0 Trifluoro-methanesulfonic acid (2R,3R,3aR,9aR)-2-(6-benzoylamino-purin-9-yl)-5,5,7,7-tetraisopropyl-tetrahydro-1,4,6,8-tetraoxa-5,7-disila-cyclopentacycloocten-3-yl ester 
• 98-88-4 benzoyl chloride 
• 4546-55-8 N-benzoyladenosine 
• 58-61-7 adenosine 
• 10457-15-5 O^2'_,O3'_,O5'-tris-trimethylsilanyl-adenosine 
• 118684-36-9 O^2;_,O3'_,O5'-tris-trimethylsilyl-N⁶-benzoyladenosine 
• 79154-57-7 3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)-N₆-benzoyladenosine 
• 69304-37-6 1,3-Dichloro-1,1,3,3-tetraisopropyldisiloxane 

Downstream Products

• 201225-45-8 N-[9-((2R,3S,4S,5R)-3-Amino-4-hydroxy-5-hydroxymethyl-tetrahydro-furan-2-yl)-9H-purin-6-yl]-benzamide 
• 201225-47-0 N-{9-[(2R,3S,4S,5R)-5-[Bis-(4-methoxy-phenyl)-phenyl-methoxymethyl]-4-hydroxy-3-(2,2,2-trifluoro-acetylamino)-tetrahydro-furan-2-yl]-9H-purin-6-yl}-benzamide 
• 201225-46-9 9-[2-amino-2-deoxy-5-O-(4,4'-dimethoxytrityl)-β-D-arabinofuranosyl]-N⁶-benzoyladenine 
• 1006062-18-5 9-[2-deoxy-5-O-(4,4'-dimethoxytrityl)-2-methoxalylamino-β-D-arabinofuranosyl]-N⁶-benzoyladenine 

Relevant academic research and scientific papers

Synthesis of fluorescein-labeled oligonucleotides bearing a tag in position 2′ of modified adenosine and arabinoadenosine

Oligonucleotide conjugates containing fluorescein residues in the sugar-phosphate back-bone were synthesized by the standard solid-phase phosphoramidite method using phosphor-amidites of 9-[2-deoxy-5-O-(4,4′- dimethoxytrityl)-2-methoxalylamino-β-D-ribofur

Synthesis and properties of modified oligodeoxyribonucleotides containing 9-(2-amino-2-deoxy-β-D-arabinofuranosyl)adenine

The synthesis of modified oligodeoxyribonucleotides containing 2'- amino-2'-deoxyarabinoadenosine residues (aA(n)) was carried out by means of the standard phosphoramidite chemistry. A high reactivity of such compounds to electrophilic reagents was shown.

Synthesis of modified oligodeoxyribonucleotides containing 9-(2′-amino-2′-deoxy-β-D-arabinofuranosyl)adenine

A method for preparing a modified derivative of 2′-amino-2′-deoxy-arabino-adenosine ready for directed insertion into an oligonucleotide chain during solid-phase synthesis was elaborated. A series of the title oligonucleotides (6-25-mers) containing a 2′-