2021-40-1

Basic information

• Product Name: vanilglycolic acid
• Synonyms: vanilglycolic acid
• CAS NO: 2021-40-1
• Molecular Formula: C₉H₈O₅
• Molecular Weight: 196.15682
• Mol File: 2021-40-1.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 395.4°Cat760mmHg
• Flash Point: 163.5°C
• Appearance: /
• Density: 1.421g/cm³
• Vapor Pressure: 5.83E-07mmHg at 25°C
• Refractive Index: 1.587
• CAS DataBase Reference: vanilglycolic acid(CAS DataBase Reference)
• NIST Chemistry Reference: vanilglycolic acid(2021-40-1)
• EPA Substance Registry System: vanilglycolic acid(2021-40-1)

Safety Data

• Hazardous Substances Data: 2021-40-1(Hazardous Substances Data)

Usage

General Description

Vanilglycolic acid, also known as 4-hydroxy-3-methoxybenzeneacetic acid, is a chemical compound that is commonly used in the fragrance and flavor industry. It is derived from vanillin, which gives it a sweet, vanilla-like aroma. Vanilglycolic acid is often used as a key ingredient in the production of perfumes, air fresheners, and beauty products. It is also known for its antioxidant properties and has been studied for its potential health benefits, including its ability to protect against oxidative stress and inflammation. vanilglycolic acid is generally considered safe for use in products but should be handled with care due to its potential to cause skin and eye irritation in high concentrations. Overall, vanilglycolic acid is a versatile chemical with a pleasant aroma and potential health benefits.

InChI:InChI=1/C9H8O5/c1-14-7-4-5(2-3-6(7)10)8(11)9(12)13/h2-4,10H,1H3,(H,12,13)

Upstream product

• 2034-60-8 1-(4-hydroxy-3-methoxy-phenyl)-propane-1,2-dione 
• 93-28-7 eugenol acetate 
• 4732-70-1 3,4-dimethoxyphenylglyoxylic acid 
• 5912-87-8 (E)-1-(4-acetoxy-3-methoxyphenyl)-1-propene 
• 860752-27-8 2-hydroxy-2-(4-hydroxy-3-methoxy-phenyl)-acetoacetic acid ethyl ester 
• 142-71-2 copper diacetate 
• 5446-97-9 bis-(4-hydroxyoxalyl-2-methoxy-phenoxy)-methane 
• 98-95-3 nitrobenzene 
• 498-02-2 1-(3-methoxy-4-hydroxyphenyl)ethanone 
• 90-05-1 2-methoxy-phenol 
• 55-10-7 4-hydroxy-3-methoxy-mandelic acid 
• 613-70-7 2-methoxyphenyl acetate 
• 97-54-1 2-methoxy-4-propenylphenol 
• 97-53-0 4-allylguaiacol 

Downstream Products

• 121-33-5 vanillin 
• 112309-82-7 C₁₅H₂₄O₅Si₂ 
• 41093-71-4 3-methoxy-4-hydroxy mandelic acid 
• 124-38-9 carbon dioxide 
• 4732-70-1 3,4-dimethoxyphenylglyoxylic acid 
• 4421-08-3 3-methoxy-4-hydroxybenzonitrile 

Relevant articles and documents

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An efficient environmentally friendly CuFe2O4/SiO2catalyst for vanillyl mandelic acid oxidation in water under atmospheric pressure and a mechanism study

With the aim of the green production of vanillin, a highly efficient environmentally friendly oxidation system was introduced to oxidize vanillyl mandelic acid (VMA) with a porous CuFe2O4/SiO2 component nano-catalyst in aqueous solution under atmospheric pressure. The N2 adsorption-desorption pattern indicated that CuFe2O4/SiO2 possessed a much higher specific surface area (49.98 m2 g-1) than that of CuFe2O4 (5.02 m2 g-1), which further indicated that the SiO2 substrate restrained the aggregation of CuFe2O4 nanoparticles. The conversion for VMA and selectivity for vanillin reached 98% and 96%, respectively, under atmospheric pressure. The excellent catalytic performance was attributed to the synergistic effect of the catalytic capacity of CuFe2O4 and the adsorption capacity for the reactant of SiO2. Simultaneously, the effect of different reaction conditions for catalyst activity and selectivity were investigated. Furthermore, the probable mechanism of VMA oxidation was investigated by in situ ATR-FTIR, H2-TPR, XPS and 1H NMR. More importantly, the decarboxylation was verified to proceed in basic conditions rather than in conventional acidic conditions. This journal is