20220-77-3

Basic information

• Product Name: Benzenamine,N,N'-methanetetraylbis[2-methoxy-
• Synonyms: Carbodiimide,bis(o-methoxyphenyl)- (6CI,7CI,8CI); NSC 97418
• CAS NO: 20220-77-3
• Molecular Formula: C15H14 N2 O2
• Molecular Weight: 254.288
• Mol File: 20220-77-3.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Benzenamine,N,N'-methanetetraylbis[2-methoxy-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenamine,N,N'-methanetetraylbis[2-methoxy-(20220-77-3)
• EPA Substance Registry System: Benzenamine,N,N'-methanetetraylbis[2-methoxy-(20220-77-3)

Safety Data

• Hazardous Substances Data: 20220-77-3(Hazardous Substances Data)

Upstream product

• 90-04-0 2-methoxy-phenylamine 
• 3288-04-8 1-isothiocyanato-2-methoxybenzene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 1226-64-8 1,3-bis-(2-methoxy-phenyl)-thiourea 
• 75-15-0 carbon disulfide 
• 56704-84-8 2-methoxy-N-(triphenylphosphoranylidene)aniline 
• 700-87-8 1-Isocyanato-2-methoxy-benzene 
• 248279-10-9 N,N'-bis-(2-methoxy-phenyl)-S-methyl-isothiourea 

Downstream Products

• 1226-63-7 1,3-bis(2-methoxyphenyl)urea 
• 84575-27-9 7-methoxy-1H-indole-2,3-dione 
• 85442-68-8 1,3-Bis-(2-methoxy-phenyl)-2-(4-phenyl-6-thioxo-1-o-tolyl-1,6-dihydro-[1,3,5]triazin-2-yl)-isothiourea; hydrochloride 
• 85442-69-9 1,3-Bis-(2-methoxy-phenyl)-2-(4-phenyl-6-thioxo-1-p-tolyl-1,6-dihydro-[1,3,5]triazin-2-yl)-isothiourea; hydrochloride 
• 85442-67-7 2-(1,4-Diphenyl-6-thioxo-1,6-dihydro-[1,3,5]triazin-2-yl)-1,3-bis-(2-methoxy-phenyl)-isothiourea; hydrochloride 

Relevant articles and documents

A facile method for the preparation of carbodiimides from thioureas and (Boc)2O

A concise method for the preparation of carbodiimides from thioureas using di-tert-butyl dicarbonate [(Boc)2O] as the dehydrosulfurizative reagent has been developed. Using DMAP as the catalyst, a variety of symmetric and asymmetric 1,3-diaryl thioureas were converted into the corresponding carbodiimides efficiently in a short time.

A greener synthetic protocol for the preparation of carbodiimide

A new and facile preparation of symmetrical and unsymmetrical 1,3-diaryl and aryl-alkyl carbodiimides via a dehydrosulfurisation of their corresponding thioureas is described. Herein, the classical method of oxidative desulfurisation of thiourea to carbodiimide involving toxic heavy metal oxides (HgO) has been replaced with an easily available, cost-effective and environmentally benign reagent, iodine. Simple reaction conditions, easy purification of the products and high yields are important attributes of the present methodology and perhaps the best alternative from a green chemistry perspective. The only limitation to this method however, is in the preparation of 1,3-dialkyl substituted carbodiimide.

A MILD AND EFFICIENT SYNTHESIS OF SYMMETRICAL DIARYL CARBODIIMIDES

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