20273-74-9

Basic information

• Product Name: α-Phenyl-4-nitrophenethyl alcohol
• Synonyms: 4-Nitro-α-phenylbenzeneethanol;α-Phenyl-4-nitrophenethyl alcohol;ALPHA-(4-NITROBENZYL)BENZYL ALCOHOL
• CAS NO: 20273-74-9
• Molecular Formula: C₁₄H₁₃NO₃
• Molecular Weight: 243.25792
• Mol File: 20273-74-9.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 398°Cat760mmHg
• Flash Point: 167.4°C
• Appearance: /
• Density: 1.26g/cm³
• Vapor Pressure: 4.76E-07mmHg at 25°C
• Refractive Index: 1.626
• CAS DataBase Reference: α-Phenyl-4-nitrophenethyl alcohol(CAS DataBase Reference)
• NIST Chemistry Reference: α-Phenyl-4-nitrophenethyl alcohol(20273-74-9)
• EPA Substance Registry System: α-Phenyl-4-nitrophenethyl alcohol(20273-74-9)

Safety Data

• Hazardous Substances Data: 20273-74-9(Hazardous Substances Data)

Usage

InChI:InChI=1/C14H13NO3/c16-14(12-4-2-1-3-5-12)10-11-6-8-13(9-7-11)15(17)18/h1-9,14,16H,10H2

Upstream product

• 100-14-1 4-nitrobenzyl chloride 
• 100-52-7 benzaldehyde 
• 100-42-5 styrene 
• 586-78-7 para-nitrophenyl bromide 
• 215254-67-4 2,2'-(1-phenylethane-1,2-diyl)dibenzo[1,3,2]dioxaborole 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 3145-86-6 4-nitrobenzyl iodide 
• 114533-06-1 (4-nitrophenyl)methyl trifluoromethanesulfonate 
• 4450-68-4 4-nitrobenzyl tosylate 
• 39834-49-6 (((4-nitrobenzyl)oxy)methanetriyl)tribenzene 
• 619-90-9 4-nitrobenzyl acetate 
• 456-27-9 4-nitrobenzenediazonium tetrafluoroborate 
• 71-43-2 benzene 
• 104-03-0 4-nitrobenzeneacetic acid 

Downstream Products

• 736-30-1 1,2-bis(4-nitrophenyl)ethane 
• 99-99-0 1-methyl-4-nitrobenzene 
• 100-52-7 benzaldehyde 
• 74127-43-8 p-nitrobenzyl hidroperoxide 
• 62-23-7 4-nitro-benzoic acid 
• 106111-26-6 1-methoxy-2-(p-nitrophenyl)-1-phenylethane 
• 114423-73-3 1-acetoxy-2-(p-nitrophenyl)-1-phenylethane 

Relevant articles and documents

Heterogeneous visible-light-induced Meerwein hydration reaction of alkenes in water using mpg-C3N4 as a recyclable photocatalyst

A green and efficient visible light induced Meerwein hydration reaction of alkenes in aqueous medium using mpg-C3N4 as a recyclabe photocatalyst has been disclosed. This protocol provides a direct approach for the preparation of racemic alcohols via a free radical mechanism. Water acted as both a solvent and a reagent without any additives or co-solvents. The metal-free heterogeneous semiconductor is found to be fully recyclable at least 5 times without any significant reduction in activity. The Meerwein hydration reaction has an excellent substrate scope and gave the desired products in moderate to high yields. Furthermore, this reaction could be carried out under solar light irradiation and is applicable for large-scale reactions with satisfactory results.

Nickel-catalyzed reductive benzylation of aldehydes with benzyl halides and pseudohalides

The reductive benzylation of aromatic and aliphatic aldehydes with benzylic halides is reported using a nickel/zinc catalyst system. In addition to benzylic halides, the first report on the addition of benzylic triflates, acetates, tosylates and tritylates to aldehydes is also presented. By this new method a range of alcohols was synthesized efficiently from aldehydes and benzylic substrates at room temperature in moderate to high yields. The mild reaction conditions and good functional group tolerance make this nickel-catalyzed process synthetically useful for the synthesis of diverse benzylic alcohols.

Original reaction of p-nitrobenzyl chloride with aldehydes using tetrakis(dimethylamino)ethylene (TDAE)

A series of disubstituted diarylethanols was prepared in moderate to good yields by reaction of p-nitrobenzyl chloride (1) with various aromatic aldehydes (2-12) in presence of tetrakis(dimethylamino)ethylene (TDAE).