3145-86-6

Basic information

• Product Name: P-NITROBENZYL IODIDE
• Synonyms: P-NITROBENZYL IODIDE;alpha-iodo-p-nitrotoluene;4-NitrobenzylIodide,>99%;1-(Iodomethyl)-4-nitrobenzene;1-Iodomethyl-4-nitrobenzene;1-Nitro-4-(iodomethyl)benzene;4-(Iodomethyl)-1-nitrobenzene;4-Nitrobenzyl iodide
• CAS NO: 3145-86-6
• Molecular Formula: C₇H₆INO₂
• Molecular Weight: 263.03
• EINECS: 221-557-8
• Mol File: 3145-86-6.mol
• Article Data: 51

Chemical Properties

• Melting Point: 124 °C
• Boiling Point: 327.5°Cat760mmHg
• Flash Point: 151.9°C
• Appearance: /
• Density: 1.928g/cm³
• CAS DataBase Reference: P-NITROBENZYL IODIDE(CAS DataBase Reference)
• NIST Chemistry Reference: P-NITROBENZYL IODIDE(3145-86-6)
• EPA Substance Registry System: P-NITROBENZYL IODIDE(3145-86-6)

Safety Data

• Hazardous Substances Data: 3145-86-6(Hazardous Substances Data)

Usage

General Description

P-Nitrobenzyl iodide is a chemical compound with the molecular formula C7H6INO2. It is an organic iodide derivative that is commonly used as a reagent in organic synthesis and as a precursor in the production of pharmaceuticals and fine chemicals. It is a yellow crystalline solid with a strong, characteristic odor. P-Nitrobenzyl iodide is a versatile compound that is used in the synthesis of a wide range of organic compounds, including pharmaceuticals, agrochemicals, and dyes. It is also a useful reagent for the protection of alcohols and amines in organic chemistry reactions. P-Nitrobenzyl iodide is a valuable tool in the modern organic synthesis toolbox, enabling the production of a diverse array of important chemical products.

Upstream product

• 100-14-1 4-nitrobenzyl chloride 
• 619-73-8 4-nitrobenzyl chloride 
• 18483-99-3 2-(4-nitrobenzyloxy)tetrahydro-2H-pyran 
• 555-16-8 4-nitrobenzaldehdye 
• 500-11-8 4-nitrobenzyl fluoride 
• 104-03-0 4-nitrobenzeneacetic acid 
• 139884-17-6 1-((methoxymethoxy)methyl)-4-nitrobenzene 
• 1058649-42-5 4-nitro-1-[(ethoxymethoxy)methyl]benzene 
• 70207-45-3 (4-nitrobenzyl)phosphoric acid diethyl ester 
• 14856-73-6 4-nitrobenzyl trimethylsilyl ether 
• 29540-08-7 tert-butyl p-nitrophenylperacetate 
• 1950-78-3 p-toluenesulfonyl iodide 
• 64-17-5 ethanol 
• 99-99-0 1-methyl-4-nitrobenzene 

Downstream Products

• 6276-18-2 2,6-dimethyl-4-(4-nitro-benzylsulfanyl)-pyrylium; iodide 
• 1835-71-8 bis(4-nitrobenzyl) sulfide 
• 1879-55-6 (E)-1-nitro-4-(prop-1-en-1-yl)benzene 
• 6921-44-4 4-nitrophenylcyclopropane 
• 3317-72-4 trans-p-nitro-(2'-methylcyclopropyl)benzene 
• 136794-71-3 4'-O-demethyl-4β-[(4''-nitrobenzyl)amino]-4-desoxypodophyllotoxin 
• 143784-71-8 di(p-nitrobenzyl) methoxycarbonylphosphonate 
• 118643-68-8 (4-Nitro-benzyl)-phenyl-phosphinic acid (4S,5R)-5-iodomethyl-2,2-dimethyl-[1,3]dioxolan-4-ylmethyl ester 
• 118643-64-4 (4-Nitro-benzyl)-phenyl-phosphinic acid (2S,3R)-4-iodo-2,3-dimethoxy-butyl ester 
• 99-99-0 1-methyl-4-nitrobenzene 
• 100-14-1 4-nitrobenzyl chloride 
• 100-11-8 1-bromomethyl-4-nitro-benzene 
• 619-93-2 (Z)-4,4'-dinitrostilbene 
• 736-31-2 trans-4,4'-dinitrostilbene 

Relevant articles and documents

Solvent-free conversion of alcohols into iodides with NaI supported on KSF clay

A variety of allylic, benzylic, primary, and secondary saturated alcohols have been converted into the corresponding iodides using NaI supported on KSF clay. Selective conversion of allylic and benzylic alcohols in the presence of primary and secondary saturated alcohols has also been demonstrated. Copyright Taylor & Francis, Inc.

Enhancing the leaving group ability of alkyl fluorides: I/F exchange reactions mediated by LiI

The carbon–fluorine (C–F) bond is one of the strongest bonds in organic chemistry and generally inert toward nucleophilic substitution reactions. To overcome the relative inertness of the C–F bond, this work focused on the ability of simple lithium salts

Rhodium-Catalyzed Generation of Anhydrous Hydrogen Iodide: An Effective Method for the Preparation of Iodoalkanes

The preparation of anhydrous hydrogen iodide directly from molecular hydrogen and iodine using a rhodium catalyst is reported for the first time. The anhydrous hydrogen iodide generated was proven to be highly active in the transformations of alkenes, phenyl aldehydes, alcohols, and cyclic ethers to the corresponding iodoalkanes. Therefore, the present methodology not only has provided convenient access to anhydrous hydrogen iodide but also offers a practical preparation method for various iodoalkanes in excellent atom economy.