204254-66-0

Basic information

• Product Name: 2-amino-4-methoxy-5-nitrobenzoic acid
• Synonyms: 2-AMINO-4-METHOXY-5-NITRO-BENZOIC ACID;Benzoic acid, 2-amino-4-methoxy-5-nitro-
• CAS NO: 204254-66-0
• Molecular Formula: C8H8N2O5
• Molecular Weight: 212.15952
• Mol File: 204254-66-0.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-amino-4-methoxy-5-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 2-amino-4-methoxy-5-nitrobenzoic acid(204254-66-0)
• EPA Substance Registry System: 2-amino-4-methoxy-5-nitrobenzoic acid(204254-66-0)

Safety Data

• Hazardous Substances Data: 204254-66-0(Hazardous Substances Data)

Upstream product

• 124-41-4 sodium methylate 
• 394-27-4 2-acetamido-4-fluorobenzoic acid 
• 446-32-2 4-fluoroanthranilic acid 
• 50868-78-5 2-acetamido-4-methoxybenzoic acid 
• 4294-95-5 4-methoxyanthranilic acid 
• 951-97-3 2-acetamido-4-nitrobenzoic acid 
• 3776-42-9 2-acetylamino-4,5-dinitro-benzoic acid 
• 875839-44-4 2-amino-4,5-dinitro-benzoic acid 

Downstream Products

• 1110813-31-4 Dacomitinib 
• 1269400-04-5 N'-(2-cyano-5-methoxy-4-nitrophenyl)-N,N-dimethylmethanimidamide 

Relevant articles and documents

Preparation method of dacomitinib intermediate

The invention provides a preparation method of a dacomitinib intermediate. The preparation method comprises steps shown in the specification. The invention provides the novel preparation method of the dacomitinib key intermediate, the intermediate is short in synthetic route, mild in reaction condition, short in reaction time and simple in separation and purification method, raw materials and reagents are conventional reagents, the cost is low, the yield of the prepared product is high, and the method is very beneficial to industrial production and popularization and has a good application prospect.