20430-09-5

Upstream product

• 110-86-1 pyridine 
• 141-82-2 malonic acid 
• 101-39-3 2-methyl-3-phenyl-2-propenal 
• 5292-43-3 bromoacetic acid tert-butyl ester 
• 122-57-6 1-Phenylbut-1-en-3-one 
• 105-36-2 ethyl bromoacetate 
• 71-43-2 benzene 
• 924-50-5 Methyl 3,3-dimethylacrylate 
• 100-52-7 benzaldehyde 
• 36678-63-4 ethoxyethynylmagnesium bromide 
• 1896-62-4 (E)-benzalacetone 
• 64245-70-1 (2Z,4E)-3-methyl-5-phenylpenta-2,4-dienal 
• 51318-62-8 ethyl 4-bromo-3-methylcrotonate 
• 7553-56-2 iodine 

Downstream Products

• 20430-13-1 (2E,4E)-3-methyl-5-phenyl-2,4-pentadienoic acid 
• 72006-15-6 3-Methyl-5-phenylpenta-2,4-dienoylchlorid 
• 29179-17-7 (3E,5Z)-4-Methyl-6-phenyl-hexa-3,5-dien-2-one 
• 29179-16-6 ethyl (2E, 4E)-3-methyl-5-phenylpenta-2,4-dienoate 
• 1364415-26-8 C₁₈H₂₄N₂O₃ 
• 1364416-13-6 C₁₉H₂₅NO₃ 
• 29179-16-6 4-methyl-6t-phenyl-hexa-3ξ,5-dien-2-one 

Relevant academic research and scientific papers

Efficient Regio- And Stereoselective Synthesis of 5-Alkyl(aryl)idene- and 5-[Iodoalkyl(aryl)idene]-1H-pyrrol-2(5//)-ones via Electrophilic Cyclization

A variety of substituted 5-alkyl(aryl)idene-and 5-[1o-doalkyl(aryl)idene]- 1ff-pyrrol-2(5H)-ones were readily prepared with good yields under very mild reaction conditions by the iodocy- clization of (2Z,4E)-dienamides and (Z)-alk-2-en-4-ynamides with iod

A survey of mono- or bis-decarboxylation of β-methyl polyethylenic-malonic acids

Diverse experimental conditions, leading to mono- or bis-decarboxylation of β-methyl polyethylenic-malonic acids, were examined. A clean and easy bis-decarboxylation was reported.

Palladium-catalysed cross-coupling of iodovinylic acids with organometallic reagents. Selective synthesis of 3,3-disubstituted prop-2-enoic acids

3,3-Disubstituted prop-2-enoic acids were selectively prepared in good yields under mild experimental conditions via palladium-catalysed cross-coupling of 3-substituted 3-iodobut-2-enoic acids with miscellaneous organometallic reagents using dichlorobis(acetonitrile)palladium(II) as catalyst and DMF as solvent.

A general synthesis of (2Z)-terpenoic acids

A three-step synthesis of (2Z), (4E)-polyenic acids 6 is described. Condensation of aldehydes 1 with potassium prenal enolate led to dihydropyranols 3 which were oxidized into dihydropyrones 5, precursors of (2Z), (4E)-polyenic acids 6. The procedure was applied to a synthesis of 13- cis-retinoic acids from β-ionylidene acetaldehydes. (C) 2000 Elsevier Science Ltd.

Pyrylium salts in polyene natural product synthesis: organometallic additions to 4-methylpyrylium tetrafluoroborate

The synthetic utility of organometallic additions to pyrylium salts as a procedure for the stereocontrolled preparation of 2Z,4E-dienals, and the use of these compounds in polyene natural product synthesis, is summarised.The extension of this methodology to 4-methylpyrylium tetrafluoroborate to give a new route to 3-methyl-2Z,4E-dienals via a six-carbon organometallic homologation procedure is then described.Finally, the utilisation of this methodology to provide a concise synthetic approach to 13Z-retinal, retinal and a range of retinal analogues is then elaborated.