206002-17-7

Usage

Uses

Used in Organic Synthesis:
2-(benzyloxy)-6-bromobenzaldehyde is utilized as a key intermediate in organic synthesis for the production of various pharmaceuticals and biologically active molecules. Its unique structure allows for a wide range of chemical reactions, facilitating the creation of diverse compounds with potential applications in medicine and other fields.
Used in Medicinal Chemistry:
In the field of medicinal chemistry, 2-(benzyloxy)-6-bromobenzaldehyde serves as a building block for the synthesis of pharmaceuticals. Its reactivity and structural features enable the development of new drugs with improved therapeutic properties.
Used in Fragrance Industry:
2-(benzyloxy)-6-bromobenzaldehyde is employed as a component in the production of fragrances. Its distinctive odor and chemical stability make it a valuable ingredient in creating various scent profiles for perfumes, cosmetics, and other fragranced products.
Used in Dye Industry:
2-(benzyloxy)-6-broMobenzaldehyde also finds application in the dye industry, where it is used in the synthesis of dyes with specific color properties. Its versatility in chemical reactions allows for the development of dyes with unique characteristics, suitable for various applications.
Used in Research and Development:
2-(benzyloxy)-6-bromobenzaldehyde is used as an intermediate in the synthesis of organic compounds for research and development purposes. Its reactivity and structural features make it an essential component in the exploration of new chemical pathways and the discovery of novel compounds with potential applications in various industries.

Upstream product

• 360575-28-6 2-bromo-6-fluorobenzaldehyde 
• 100-51-6 benzyl alcohol 
• 22532-61-2 2-bromo-6-hydroxybenzaldehyde 
• 863870-72-8 O-3-bromophenyl N,N-diethylcarbamate 
• 100-39-0 benzyl bromide 
• 124639-28-7 2-(2-methoxyphenyl)-1,3-dimethylimidazolidine 
• 135-02-4 ortho-anisaldehyde 
• 126712-07-0 2-bromo-6-methoxybenzaldehyde 

Downstream Products

• 206002-16-6 (E)-3-[(2-(benzyloxy)-6-bromophenyl)methylene]-2,3-dihydro-5,6-dimethoxy-2-[(4-methoxyphenyl)methyl]-1H-isoindol-1-one 
• 1135492-35-1 3-(2-(benzyloxy)-6-bromophenyl)-2-cyanoacrylic acid 
• 1334396-07-4 2-(allyloxymethyl)-1-(benzyloxy)-3-bromobenzene 
• 1334396-22-3 C₄₉H₇₆O₆Si₂ 
• 1334396-06-3 (2S)-2-((S)-(2-(allyloxy)-6-((tert-butyldimethylsilyloxy)methyl)phenyl)(triethylsilyloxy)methyl)-1-(2-(allyloxymethyl)-3-(benzyloxy)phenyl)nonanone 
• 1334396-17-6 (((3R,4S)-4'-(benzyloxy)-3-heptyl-4-(triethylsilyloxy)-3'H-spiro[chroman-2,1'-isobenzofuran]-5-yl)methoxy)(tert-butyl)dimethylsilane 
• 1410804-93-1 ((2-(benzyloxy)-6-bromophenyl)ethynyl)trimethylsilane 
• 1410804-98-6 (R)-3-(3-(benzyloxy)-2-ethynylphenyl)-1-bromo-3-((2-(trimethylsilyl)ethoxy)methoxy)-butan-2-one 
• 1410804-95-3 (R)-3-(3-(benzyloxy)-2-ethynylphenyl)-3-hydroxybutan-2-one 
• 1410805-59-2 (4R,5S)-4-(3-(benzyloxy)-2-ethynylphenyl)-2,2,4,5-tetramethyl-1,3-dioxolane 
• 1410805-64-9 C₄₇H₆₀N₂O₁₁Si₂ 
• 1410805-53-6 C₄₆H₅₆N₂O₉Si₂ 
• 1410805-60-5 (2R,3R)-2-(3-(benzyloxy)-2-ethynylphenyl)-2,3-dimethyloxirane 

Relevant academic research and scientific papers

7- OR 8-HYDROXY-ISOQUINOLINE AND 7- OR 8-HYDROXY-QUINOLINE DERIVATIVES AS ALPHA-1 -ANTITRYPSIN MODULATORS FOR TREATING ALPHA-1 -ANTITRYPSIN DEFICIENCY (AATD)

7- or 8-hydroxy-isoquinoline and 7- or 8-hydroxy-quinoline derivatives as alpha-l-antitrypsin modulators for treating alpha-l-antitrypsin deficiency (AATD).

BIARYL DERIVATIVES AS YAP/TAZ-TEAD PROTEIN-PROTEIN INTERACTION INHIBITORS

The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof; (I) a method for manufacturing said compound, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition comprising said compound.

Atroposelective Synthesis of Axially Chiral 4-Aryl α-Carbolines via N-Heterocyclic Carbene Catalysis

The first catalytic asymmetric construction of axially chiral 4-aryl α-carboline skeletons has been accomplished through an N-heterocyclic carbene (NHC)-catalyzed atroposelective formal [3 + 3] annulation of 4-nitrophenyl 3-arylpropiolates with 2-sulfonamidoindolines. The synthetic utility of the title compounds has been demonstrated by the diverse late-stage structural modifications. Density functional theory calculations were also conducted to illuminate the key factors for controlling the origin of the enantioselectivity. This strategy not only provides an efficient pathway to access axially chiral α-carboline atropisomers but also offers a novel catalytic enantioselective mode for the construction of axially chiral heterobiaryls by using NHC-bound alkynyl acylazoliums.

A macrocyclic approach to tetracycline natural products. Investigation of transannular alkylations and Michael additions

A new approach to the tetracycline core structure is presented. The pivotal intermediate is identified as macrocycle III. The two interior bonds (C4a-C12a and C5a-C11a) are to be constructed through sequential transannular Michael additions (III-II) and compression-promoted transannular isoxazole alkylations from intermediate II.

Total synthesis of paecilospirone

Neutrality is the best policy: Key features of the first total synthesis of paecilospirone include an anti-selective, lactate-derived aldol reaction, and a double deallylation/spirocyclization conducted at neutral pH to construct the sensitive hydroxy-substituted benzannulated spiroacetal (see scheme; Bn=benzyl, TBS=tert-butyldimethylsilyl, TES=triethylsilyl).

TRICYCLIC HETEROCYCLIC DERIVATIVES

The present invention relates to a tricyclic heterocyclic derivative of Formula (I) wherein the variables are as defined in the specification. The present invention further relates to pharmaceutical compositions comprising these compounds and to their use in therapy, in particular for the treatment of serotonin-mediated disorders such as obesity, schizophrenia and cognitive dysfunction.