206358-62-5

Basic information

• Product Name: Bzl-D-Nle-OMe
• Synonyms: Bzl-D-Nle-OMe
• CAS NO: 206358-62-5
• Molecular Formula: C14H21NO2
• Molecular Weight: 235.32
• Mol File: 206358-62-5.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bzl-D-Nle-OMe(CAS DataBase Reference)
• NIST Chemistry Reference: Bzl-D-Nle-OMe(206358-62-5)
• EPA Substance Registry System: Bzl-D-Nle-OMe(206358-62-5)

Safety Data

• Hazardous Substances Data: 206358-62-5(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 206358-56-7 (4S,5R)-1-((R)-2-Benzylamino-hexanoyl)-3,4-dimethyl-5-phenyl-imidazolidin-2-one 
• 206358-48-7 (2'RS,4S,5R)-1-N-(2'bromohexanoyl)-3,4-dimethyl-5-phenylimidazolidin-2-one 
• 100-46-9 benzylamine 
• 445298-99-7 (S,S)-N-methylpseudoephedrine α-bromo-α-n-butylacetate 
• 622-79-7 benzyl azide 
• 81801-15-2 (R)-(E)-3-octen-2-ol 
• 100-39-0 benzyl bromide 
• 3844-54-0 L-2-aminohexanoic acid-methyl ester hydrochloride 

Relevant articles and documents

Synthesis of functionalized, unsymmetrical 1,3,4,6-tetrasubstituted 2,5-diketopiperazines

A general and efficient method for the synthesis of unsymmetrical 1,3,4,6-tetrasubstituted 2,5-diketopiperazines (DKPs) is described. Cyclization of N-amide alkylated dipeptide methyl esters, followed by alkylation, furnished the corresponding tetrasubsti

Dynamic resolution of α-bromo-α-alkyl esters using N-methyl pseudoephedrine as a chiral auxiliary: Asymmetric syntheses of α-amino acid derivatives

N-Methyl pseudoephedrine mediated dynamic resolution of α-bromo-α-alkyl esters in nucleophilic substitution reaction has been investigated. Best results are obtained when α-bromo-α-alkyl esters 1, 4 and 5 are allowed to equilibrate before the addition of nucleophile. This simple epimerization-substitution sequence provides a practical protocol for asymmetric syntheses of α-amino acid derivatives 2, 7 and 8 up to 98:2 enantiomeric ratio.