2068-83-9Relevant articles and documents
Palladium-catalyzed β-acyloxylation of simple amide via sp3 C-H activation
Zhou, Lihong,Lu, Wenjun
supporting information, p. 508 - 511 (2014/04/03)
β-Acyloxy amides are prepared in moderate to high yields by palladium-catalyzed acyloxylation of primary sp3 C-H bonds from simple amides without any special directing group. A catalytic system of Pd(OAc)2/CF3CO2H/ K2S2O8 is available to various amides with N-substituted by linear alkanes, cyclic alkanes, and electron-deficient benzyl compounds in this reaction. Acyloxylated products could be transformed easily to the corresponding β-hydroxy amides.
Oxidative esterification of homologous 1,3-propanediols
Kotionova, Tatyana,Lee, Christopher,Miedziak, Peter J.,Dummer, Nicholas F.,Willock, David J.,Carley, Albert F.,Morgan, David J.,Knight, David W.,Taylor, Stuart H.,Hutchings, Graham J.
, p. 1114 - 1120 (2012/10/29)
The oxidative esterification of a homologous series of diols (1,3-propanediol,2-methyl-propanediol and 2,2-dimethyl-1,3-propanediol) with methanol has been investigated using titania-supported gold, palladium and gold-palladium catalysts using molecular oxygen. The gold-palladium catalysts showed the highest activity and 1,3-propanediol was the most reactive while the additional methyl groups decreased the reactivity. However, it is possible to achieve high selectivity to methyl 3-hydroxypropionate and 2-methyl-3- hydroxyisobutyrate by mono-oxidations. Graphical Abstract: [Figure not available: see fulltext.]
Bioactive constituents from chinese natural medicines. XXXI.1 hepatoprotective principles from sinocrassula indica: Structures of sinocrassosides A8, A9, A10, A11, and A12
Ninomiya, Kiyofumi,Morikawa, Toshio,Xie, Haihui,Matsuda, Hisashi,Yoshikawa, Masayuki
experimental part, p. 1983 - 1995 (2009/04/06)
The methanolic extract from the whole plant of Sinocrassula indica (Crassulaceae) was found to show hepatoprotective effect on D-galactosamineinduced cytotoxicity in primary cultured mouse hepatocytes. From the methanolic extract, five new acylated flavon