207386-32-1Relevant academic research and scientific papers
Coupling of alkynylTMS derivatives with vinylic iodides. An efficient route to 1,3-enynes and dienes
Marshall, James A.,Chobanian, Harry R.,Yanik, Mathew M.
, p. 4107 - 4110 (2007/10/03)
matrix presented CuCl-promoted coupling of alkynylTMS derivatives with vinyl iodides leads to 1,3-enynes in high yield. Enynes prepared from homopropargylic alcohols undergo intramolecular hydrosilylation and subsequent silyl cleavage with TBAF to afford
Acid-catalyzed cyclization of vinylsilanes bearing a hydroxy group: A new method for stereoselective synthesis of disubstituted tetrahydrofurans
Miura,Okajima,Hondo,Nakagawa,Takahashi,Hosomi
, p. 11348 - 11357 (2007/10/03)
In the presence of a catalytic amount of TsOH or TiCl4, (Z)-5-silyl-4-penten-1-ols ((Z)-1) are smoothly cyclized to 2-silylmethyl-substituted tetrahydrofurans. This cyclization is applicable to the construction of a tetrahydropyran ring. The silyl group and the geometry of the C-C double bond strongly influence the cychzation rate. TBDMS and benzyldimethylsilyl groups considerably accelerate the cyclization in comparison with a dimethylphenylsilyl group, and (E)-vinylsilanes show much lower reactivity than the corresponding (Z)-isomers. The cyclization proceeds by stereospecific syn addition of the hydroxy group. Vinylsilanes 17, 19, and 21, (Z)-5-silyl-4-penten-1-ols bearing a substituent on the methylene tether, smoothly undergo the acid-catalyzed cyclization to give trans-2,5-, cis-2,4-, and trans-2,3-disubstituted tetrahydrofurans, respectively, with moderate to high stereoselectivity. The silyl group of some cychzed products can be easily converted into a hydroxy group with stereochemical retention.
Novel decomplexation method for alkyne-Co2(CO)6 complexes
Sugihara, Takumichi,Ban, Hitoshi,Yamaguchi, Masahiko
, p. 163 - 166 (2007/10/03)
A novel and general decomplexation method for alkyne-Co2(CO)6 complexes has been established, which treats the complexes with ethylenediamine in THF.
