20754-22-7

Basic information

• Product Name: METHYL 4-TRIFLUOROMETHYLCINNAMATE
• Synonyms: METHYL 4-TRIFLUOROMETHYLCINNAMATE;4-(Trifluoromethyl)-cinnamic methyl ester;(E)-Methyl 3-(4-(trifluoroMethyl)phenyl)acrylate;Methyl (E)-(4-Trifluoromethyl)cinnamate;2-Propenoic acid,3-[4-(trifluoromethyl)phenyl]-, methyl ester, (2E)-
• CAS NO: 20754-22-7
• Molecular Formula: C₁₁H₉F₃O₂
• Molecular Weight: 230.18
• Mol File: 20754-22-7.mol
• Article Data: 56

Chemical Properties

• Boiling Point: 256.8°Cat760mmHg
• Flash Point: 91.4°C
• Appearance: /
• Density: 1.251g/cm³
• Vapor Pressure: 0.015mmHg at 25°C
• Refractive Index: 1.494
• CAS DataBase Reference: METHYL 4-TRIFLUOROMETHYLCINNAMATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 4-TRIFLUOROMETHYLCINNAMATE(20754-22-7)
• EPA Substance Registry System: METHYL 4-TRIFLUOROMETHYLCINNAMATE(20754-22-7)

Safety Data

• Hazardous Substances Data: 20754-22-7(Hazardous Substances Data)

Usage

General Description

Methyl 4-trifluoromethylcinnamate is a chemical compound with the molecular formula C11H9F3O2. It is a clear, colorless to pale yellow liquid with a sweet, floral odor. METHYL 4-TRIFLUOROMETHYLCINNAMATE is commonly used in the fragrance and flavor industry as a synthetic flavoring agent, as well as in the production of perfumes and cosmetic products. It is also used as an intermediate in the synthesis of pharmaceuticals and agrochemicals. Methyl 4-trifluoromethylcinnamate has been found to exhibit antimicrobial and antifungal properties, and it is also used as an insecticide and acaricide in agricultural applications. Additionally, it has potential applications in the field of organic electronics and optoelectronic devices.

InChI:InChI=1/C11H9F3O2/c1-16-10(15)7-4-8-2-5-9(6-3-8)11(12,13)14/h2-7H,1H3/b7-4+

Upstream product

• 2062-26-2 3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 79-20-9 acetic acid methyl ester 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 21204-67-1 methyl (triphenylphosphoranylidene)acetate 
• 88738-78-7 bis-(2,2,2-trifluoroethyl)(methoxycarbonylmethyl)phosphonate 
• 5927-18-4 trimethyl phosphonoacetate 
• 292638-85-8 acrylic acid methyl ester 
• 16695-14-0 Malonic acid monomethyl ester 
• 67-56-1 methanol 
• 105919-36-6 trans-4-(trifluoromethyl)cinnamoyl chloride 
• 1189365-73-8 quinolin-8-yl(4-(trifluoromethyl)phenyl)methanone 
• 1529-78-8 [(methoxycarbonyl)methyl]triphenylarsonium bromide 
• 2967-66-0 methyl 4-(trifluoromethyl)benzoate 

Downstream Products

• 20754-22-7 methyl (Z)-3-(4-trifluoromethylphenyl)acrylate 
• 849442-21-3 methyl 3-(4-(trifluoromethyl)phenyl)propanoate 
• 125617-18-7 3-(4-trifluoromethylphenyl)-2-propen-1-ol 
• 2062-26-2 3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid 
• 955137-85-6 (+/-)-trans-1-(tert-butoxycarbonyl)-4-(4-(trifluoromethyl)-phenyl)pyrrolidine-3-carboxylic acid 
• 1227844-91-8 (3S,4R)-1-(tert-butoxycarbonyl)-4-(4-trifluoromethylphenyl)pyrrolidine-3-carboxylic acid 
• 1227844-93-0 (3R,4S)-1-(tert-butoxycarbonyl)-4-(4-trifluoromethylphenyl)pyrrolidine-3-carboxylic acid 
• 180635-74-9 3‐(4‐(trifluoromethyl)phenyl)propan‐1‐ol 

Relevant articles and documents

A cross-linked reverse micelle-encapsulated palladium catalyst

Cross-linked reverse micelle-palladium catalysts are effective and stable cross-coupling catalysts; cross-linking is crucial for stability. The Royal Society of Chemistry 2005.

Oxoammonium-Mediated Allylsilane–Ether Coupling Reaction

A new C(sp3)?H functionalization reaction consisting of the oxidative α-allylation of allyl- and benzyl- methyl ethers has been developed. The C?C coupling could be carried out under mild conditions thanks to the use of cheap and green oxoammonium salts. The scope of the reaction was studied over 27 examples, considering the nature of the substituents on the two coupling partners.

Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures, irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility. (Figure presented.).