849442-21-3

Basic information

• Product Name: Benzenepropanoic acid, 4-(trifluoroMethyl)-, Methyl ester
• Synonyms: Benzenepropanoic acid, 4-(trifluoroMethyl)-, Methyl ester
• CAS NO: 849442-21-3
• Molecular Formula: C₁₁H₁₁F₃O₂
• Molecular Weight: 232.1990496
• Mol File: 849442-21-3.mol
• Article Data: 21

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzenepropanoic acid, 4-(trifluoroMethyl)-, Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzenepropanoic acid, 4-(trifluoroMethyl)-, Methyl ester(849442-21-3)
• EPA Substance Registry System: Benzenepropanoic acid, 4-(trifluoroMethyl)-, Methyl ester(849442-21-3)

Safety Data

• Hazardous Substances Data: 849442-21-3(Hazardous Substances Data)

Upstream product

• 53473-36-2 3-(4-trifluoromethylphenyl)propionic acid 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 67-56-1 methanol 
• 79947-88-9 methyl 4-trifluoromethylcinnamate 
• 20754-22-7 methyl (2E)-3-(4-(trifluoromethyl)phenyl)prop-2-enoate 
• 73183-34-3 bis(pinacol)diborane 
• 402-50-6 1-trifluoromethyl-4-vinyl-benzene 
• 124-38-9 carbon dioxide 
• 74-88-4 methyl iodide 
• 2062-26-2 3-<4'-(trifluoromethyl)phenyl>-2-propenoic acid 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 1942-46-7 5-decyne 
• 128796-39-4 4-trifluoromethylphenylboronic acid 
• 292638-85-8 acrylic acid methyl ester 

Downstream Products

• 769172-66-9 N-[2-(3,4-dimethoxy-phenyl)-ethyl]-3-(4-trifluoromethyl-phenyl)-propionamide 
• 528867-43-8 4-(4-(trifluoromethyl)phenyl)butanal 
• 166947-09-7 3-(4-trifluoromethylphenyl)propanal 

Relevant articles and documents

Reduction of Electron-Deficient Alkenes Enabled by a Photoinduced Hydrogen Atom Transfer

Direct hydrogen atom transfer from a photoredox-generated Hantzsch ester radical cation to electron-deficient alkenes has enabled the development of an efficient formal hydrogenation under mild, operationally simple conditions. The HAT-driven mechanism is supported by experimental and computational studies. The reaction is applied to a variety of cinnamate derivatives and related structures, irrespective of the presence of electron-donating or electron-withdrawing substituents in the aromatic ring and with good functional group compatibility. (Figure presented.).

Iron-catalysed 1,2-aryl migration of tertiary azides

1,2-Aryl migration of α,α-diaryl tertiary azides was achieved by using the catalytic system of FeCl2/N-heterocyclic carbene (NHC) SIPr·HCl. The reaction generated aniline products in good yields after one-pot reduction of the migration-resultant imines.

Diboron-Mediated Rhodium-Catalysed Transfer Hydrogenation of Alkenes and Carbonyls

A diboron-mediated rhodium-catalysed transfer hydrogenation system using water as the hydrogen donor is developed. In addition to a series of alkenes with good functional group tolerance, this rhodium-based catalytic system also effectively reduces aldehydes and ketones. A plausible mechanism involving the RhI-catalysed hydrogen generation and Rh0-catalysed hydrogenation is proposed for the reaction.