209169-05-1

Basic information

• Product Name: 2-(6-bromo-1H-indol-3-yl)-N-methylethanamine
• Synonyms: 2-(6-bromo-1H-indol-3-yl)-N-methylethanamine
• CAS NO: 209169-05-1
• Molecular Formula: C₁₁H₁₃BrN₂
• Molecular Weight: 253.13832
• Mol File: 209169-05-1.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-(6-bromo-1H-indol-3-yl)-N-methylethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(6-bromo-1H-indol-3-yl)-N-methylethanamine(209169-05-1)
• EPA Substance Registry System: 2-(6-bromo-1H-indol-3-yl)-N-methylethanamine(209169-05-1)

Safety Data

• Hazardous Substances Data: 209169-05-1(Hazardous Substances Data)

Usage

Derivative of indole

The compound is based on the indole structure, which is a heterocyclic aromatic compound commonly found in plants and animals.

Contains a bromine atom

The presence of bromine in the compound can affect its physical and chemical properties, such as solubility and reactivity.

Methylated amine group

The compound has a methyl group attached to an amine group, which can influence its pharmacological properties.

Potential applications in medicinal chemistry and drug development

The compound has potential for use in the synthesis of new psychoactive substances and pharmaceutical drugs targeting the central nervous system.

Research applications in the study of serotonin receptors

The compound may be useful in studying serotonin receptors and related biochemical pathways.

Upstream product

• 52415-29-9 6-bromo-1H-indole 
• 79-37-8 oxalyl dichloride 
• 74-89-5 methylamine 
• 1912-33-0 Indole-3-acetic acid methyl ester 
• 1352956-47-8 methyl 6-bromo-2-(1,1-dimethylallyl)-3-indoleacetate 
• 947605-02-9 methyl (2,6-dibromo-1H-indol-3-yl)acetate 
• 2054-72-0 2-(1H-indol-3-yl)-N-methyl-2-oxoacetamide 

Downstream Products

• 474657-72-2 Desformylflustrabromine 
• 847549-20-6 N-{2-[6-bromo-3-(1,1-dimethyl-allyl)-1-(3-methyl-but-2-enyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-ethyl}-N-methyl-4-nitro-benzenesulfonamide 
• 847549-22-8 N-{2-[6-bromo-3-(1,1-dimethyl-allyl)-2-methoxy-3H-indol-3-yl]-ethyl}-N-methyl-4-nitro-benzenesulfonamide 
• 847549-19-3 N-{2-[6-bromo-3-(1,1-dimethyl-allyl)-2-oxo-2,3-dihydro-1H-indol-3-yl]-ethyl}-N-methyl-4-nitro-benzenesulfonamide 
• 847549-18-2 N-[2-(3,6-dibromo-2-oxo-2,3-dihydro-1H-indol-3-yl)-ethyl]-N-methyl-4-nitro-benzenesulfonamide 
• 847549-17-1 N-[2-(6-bromo-1H-indol-3-yl)-ethyl]-N-methyl-4-nitro-benzenesulfonamide 

Relevant articles and documents

Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator

Desformylflustrabromine (dFBr; 1) and desformylflustrabromine-B (dFBr-B; 2) have been previously isolated from natural sources, and the former has been demonstrated to be a novel and selective positive allosteric modulator of α4β2 nicotinic acetylcholine (nACh) receptors. The present study describes the synthesis of water-soluble salts of 1 and 2, and confirms and further investigates the actions of 1 and 2 using two-electrode voltage clamp recordings.

Concise synthesis of deformylflustrabromine, a marine indole alkaloid, through a 2-propynyl dicobalt hexacarbonyl complex

Deformylflustrabromine, a marine indole alkaloid, was synthesized from 6-bromotryptamine, a plausible biosynthetic precursor, without protection of the amino group by a two-step reverse prenylation involving the Nicholas reaction and reductive decomplexat