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2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

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  • 21132-02-5 Structure
  • Basic information

    1. Product Name: 2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE
    2. Synonyms: CHEMBRDG-BB 5868074;2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE;AKOS BBV-005771;OTAVA-BB 1133402;UKRORGSYN-BB BBV-005771;2-amino-N-(2,4-dimethylphenyl)benzamide(SALTDATA: FREE)
    3. CAS NO:21132-02-5
    4. Molecular Formula: C15H16N2O
    5. Molecular Weight: 240.3
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 21132-02-5.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 335.5°C at 760 mmHg
    3. Flash Point: 156.7°C
    4. Appearance: /
    5. Density: 1.182g/cm3
    6. Vapor Pressure: 0.000119mmHg at 25°C
    7. Refractive Index: 1.656
    8. Storage Temp.: N/A
    9. Solubility: N/A
    10. CAS DataBase Reference: 2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE(CAS DataBase Reference)
    11. NIST Chemistry Reference: 2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE(21132-02-5)
    12. EPA Substance Registry System: 2-AMINO-N-(2,4-DIMETHYLPHENYL)BENZAMIDE(21132-02-5)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 21132-02-5(Hazardous Substances Data)

21132-02-5 Usage

Also known as

N-(2,4-dimethylphenyl)anthranilic acid

Class

benzamides

Commonly used in

pharmaceutical industry

Role

intermediate in the synthesis of pharmaceutical drugs
Potential therapeutic applications
Being studied for pharmacological properties
Function and mode of action depend on specific context
Ongoing research to explore potential uses

Check Digit Verification of cas no

The CAS Registry Mumber 21132-02-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 2,1,1,3 and 2 respectively; the second part has 2 digits, 0 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 21132-02:
(7*2)+(6*1)+(5*1)+(4*3)+(3*2)+(2*0)+(1*2)=45
45 % 10 = 5
So 21132-02-5 is a valid CAS Registry Number.
InChI:InChI=1/C15H16N2O/c1-10-7-8-14(11(2)9-10)17-15(18)12-5-3-4-6-13(12)16/h3-9H,16H2,1-2H3,(H,17,18)

21132-02-5Relevant articles and documents

Sustainable methine sources for the synthesis of heterocycles under metal- and peroxide-free conditions

Senadi, Gopal Chandru,Kudale, Vishal Suresh,Wang, Jeh-Jeng

supporting information, p. 979 - 985 (2019/03/12)

Alcohols and ethers were identified as sustainable methine sources for synthesizing quinazolinone and benzimidazole derivatives using a combination of TsOH·H2O/O2 and appropriate bis-nucleophiles for the first time. Deuterium labeling studies clearly proved that the C2 hydrogen of the synthesized heterocycles came from the methine source. These unique reaction conditions were successfully applied to the synthesis of echinozolinone (2e′), 2f′ (a common precursor of rutaecarpine and (±) evodiamine), and dimedazole (6d). Notable features of this method include its low toxicity, use of commercial feedstocks as substrates, low cost, broad functional group tolerance and suitability for a wide range of bis-nucleophilic starting materials.

Sulfur-Promoted Synthesis of 2-Aroylquinazolin-4(3H)-ones by Oxidative Condensation of Anthranilamide and Acetophenones

Nguyen, Thanh Binh,Hou, Jing-ya,Retailleau, Pascal

, p. 3337 - 3341 (2019/06/13)

A sulfur-promoted three-component reaction of isatoic anhydride, primary aliphatic or aromatic amines, and acetophenones leading to densely substituted 3-substituted 2-aroylquinazolin-4(3H)-ones is reported. The key step involves a cascade reaction of selective oxidation of the methyl group of the acetophenones, followed by a condensation with anthranilamides. The scope of the reaction is applicable to the synthesis of tryptanthrin and various 3-unsubstituted 2-aroylquinazolin-4(3H)-ones. (Figure presented.).

Synthesis, antimicrobial evaluation, ot-QSAR and mt-QSAR studies of 2-amino benzoic acid derivatives

Mahiwal, Kuldeep,Kumar, Pradeep,Narasimhan, Balasubramanian

experimental part, p. 293 - 307 (2012/09/07)

A series of 2-amino benzoic acid derivatives (1-28) were synthesized and evaluated for their in vitro antimicrobial activity against the panel of Gram positive, Gram negative bacterial and fungal strains. The results of antimicrobial studies indicated that, in general, the synthesized compounds were found to be bacteriostatic and fungistatic in action. QSAR studies performed by the development of one target and multi target models indicated that multi-target model was effective in describing the antimicrobial activity as well demonstrated the effect of structural parameters viz. LUMO, 3χv and W on antimicrobial activity of 2-amino benzoic acid derivatives. Springer Science+Business Media, LLC 2010.

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