21292-26-2

Upstream product

• 100-47-0 benzonitrile 
• 65-85-0 benzoic acid 

Downstream Products

• 130114-63-5 Benzoic acid (3R,4S,5S)-5-benzyloxymethyl-4-hydroxy-5-methoxy-tetrahydro-furan-3-yl ester 
• 55-21-0 benzamide 
• 337376-51-9 (1S,2S)-benzoic acid 1-hydroxy-1,2-dihydronaphthalen-2-yl-ester 
• 337376-51-9 (1R,2R)-benzoic acid 1-hydroxy-1,2-dihydronaphthalen-2-yl-ester 
• 746652-57-3 (2R,3R)-benzoic acid 1-benzyloxymethyl-3,3,3-trifluoro-2-hydroxypropyl ester 
• 746652-58-4 (2S,3S)-benzoic acid 1-benzyloxymethyl-3,3,3-trifluoro-2-hydroxypropyl ester 
• 883746-36-9 (1R,2R)-benzoic acid 2-(1R,2S,5R)-(2-isopropyl-5-methylcyclohexyloxycarbonylamino)cyclohex-3-enyl ester 
• 883746-38-1 (1S,2S)-benzoic acid 2-(1R,2S,5R)-(2-isopropyl-5-methylcyclohexyloxycarbonylamino)cyclohex-3-enyl ester 

Relevant academic research and scientific papers

Synthesis, characterization, and thermodynamic study of ammonium benzoate C7H5O2NH4(s)

Benzoic acid and concentrated ammonia were chosen as reactants and a novel compound (ammonium benzoate) was synthesized using the method of liquid phase reaction. FTIR, elemental analysis and X-ray powder diffraction technique were applied to characterize the structure and composition of the compound. Low-temperature heat capacities of the solid compound were measured by a precision automated adiabatic calorimeter over the temperature range from 80 to 399 K. A polynomial equation of the heat capacities was fitted by the least-squares method. In accordance with Hess' law, a thermochemical cycle was designed, the enthalpy change of the reaction of benzoic acid with ammonium acetate was determined as Δr Hm ° = (15.59 ± 0.50) kJ mo l- 1, and the standard molar enthalpy of formation of the compound was calculated as Δf Hm ° [ C7 H5 O2 N H4,s ] = - (472.65 ± 0.62) kJ mo l- 1 by an isoperibol solution-reaction calorimeter.

Green synthesis method of aromatic acid

The invention relates to a synthesis method of organic acid, in particular to a green synthesis method of aromatic acid, and belongs to the field of organic synthesis. According to the green synthesismethod of the aromatic acid, an aromatic cyano compound is used as a substrate, a corresponding aromatic acid ammonium salt is obtained after catalytic hydrolysis under catalysis of an alkali catalyst, the obtained aromatic acid ammonium salt is hydrolyzed to obtain the aromatic acid, at the same time, byproduct ammonia water is produced, and the alkali catalyst can be repeatedly applied for manytimes; and the structural formula of the aromatic cyano compound is as follows (please see the specification for the formula). The green synthesis method has the characteristics of simple operation,high product yield, easy separation and basically no generation of salt containing wastewater, small generation amount of wastewater, environmental friendliness and the like, in addition, the catalystcan further be reused for many times, and after repeated application of the catalyst, the total yield of a product can be close to 100%.