213699-53-7

Basic information

• Product Name: 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl-
• Synonyms: 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl-
• CAS NO: 213699-53-7
• Molecular Formula: C₁₅H₁₇NO₆
• Molecular Weight: 307.29858
• Mol File: 213699-53-7.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl-(213699-53-7)
• EPA Substance Registry System: 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl-(213699-53-7)

Safety Data

• Hazardous Substances Data: 213699-53-7(Hazardous Substances Data)

Usage

General Description

1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- is a chemical compound with the molecular formula C15H17NO4. It is a derivative of dioxane and contains a diMethoxyphenyl group. 1,3-Dioxane-4,6-dione, 5-[[(3,4-diMethoxyphenyl)aMino]Methylene]-2,2-diMethyl- is often used in organic synthesis and pharmaceutical research due to its potential medicinal properties. It may have applications in the development of new medications or as an intermediate in the production of other chemicals. Additionally, the diMethoxyphenyl group could impart specific biological activities to the compound, making it of interest for further study.

Upstream product

• 15568-85-1 5-methoxymethylene-2,2-dimethyl-1,3-dioxane-4,6-dione 
• 6315-89-5 3,4-dimethoxyaniline 
• 2033-24-1 cycl-isopropylidene malonate 
• 149-73-5 trimethyl orthoformate 
• 122-51-0 orthoformic acid triethyl ester 

Downstream Products

• 13425-93-9 6,7-dimethoxyquinoline-4-ol 
• 190728-24-6 6,7?dimethoxy?4?(4?nitrophenoxy)quinoline 
• 190728-25-7 4-((6,7-dimethoxyquinolin-4-yl)oxy)aniline 
• 286371-44-6 4-[(6,7-Dimethoxy-4-quinolyl)oxy]-2-chloroaniline 
• 1437323-99-3 4-(6,7-dimethoxyquinolin-4-yloxy)-2,3-difluorophenylamine 
• 347161-74-4 4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluoroaniline 
• 516526-44-6 4-(2-fluoro-4-nitro-phenoxy)-6,7-dimethoxy-quinoline 
• 35654-56-9 6,7-dimethoxy-4-chloroquinoline 
• 127285-54-5 1,4-dihydro-6,7-dimethoxy-4-oxoquinoline 
• 848128-82-5 5,6-dimethoxy-quinolin-4-ol 

Relevant articles and documents

N-(5-phenyl-1, 3, 4-thiadiazole-2-yl) benzamide compound

The invention belongs to the technical field of medicines, relates to a compound with antitumor activity and a specific chemical structure, and in particular relates to an N-((6, 7-dimethoxyquinoline-4-yl) oxy) methyl)-N-(5-phenyl-1, 3, 4-thiadiazole-2-yl) benzamide compound and a preparation method and an application thereof. The structural general formula of the compound is shown in the specification, wherein an R group is mono-substituted or double-substituted phenyl, fluorophenyl, chlorphenyl, bromophenyl, benzyl, benzyloxy, benzene nitro or trifluoromethyl substituted at 2-position, 3-position or 4-position. Pharmacological studies show that the compound provided by the invention has a relatively remarkable proliferation inhibition effect on HER-2 positive breast cancer cells SK-Br-3, the effect is obviously superior to that of HER-2 negative breast cancer cells MCF-7, the compound can be used for preparing antitumor drugs, and a new way is opened up for deep research and development of tumor drugs in the future. The preparation method provided by the invention is simple and feasible, relatively high in yield and easy for large-scale production.

SUBSTITUTED QUINOLINE COMPOUNDS AND METHODS OF USE

The present invention provides novel substituted quinoline compounds, pharmaceutical acceptable salts and formulations thereof useful in modulating the protein tyrosine kinase activity, and in modulating cellular activities such as proliferation, differentiation, apoptosis, migration and invasion. The invention also provides pharmaceutically acceptable compositions comprising such compounds and methods of using the compositions in the treatment of hyperproliferative disorders in mammals, especially humans.

INHIBITORS OF PROTEIN TYROSINE KINASE ACTIVITY

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