21399-34-8

Basic information

• Product Name: (1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine
• CAS NO: 21399-34-8
• Molecular Formula: C₁₈H₂₀N₂O₂
• Molecular Weight: 296.3636
• Mol File: 21399-34-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 402.68°C at 760 mmHg
• Flash Point: 159.411°C
• Density: 1.043g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: (1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine(CAS DataBase Reference)
• NIST Chemistry Reference: (1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine(21399-34-8)
• EPA Substance Registry System: (1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine(21399-34-8)

Safety Data

• Hazardous Substances Data: 21399-34-8(Hazardous Substances Data)

Usage

General Description

"(1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine" is a chemical compound with the molecular formula C16H20N2O. It is an organic compound that belongs to the class of hydrazines, which are nitrogen-containing compounds. This specific compound is a bis-hydrazine, meaning it contains two hydrazine functional groups. The presence of the (1E)-bis[1-(4-methoxyphenyl)ethylidene] groups in the molecule indicates the presence of a specific type of carbon-carbon double bond. (1E)-bis[1-(4-methoxyphenyl)ethylidene]hydrazine has potential applications in organic synthesis and may have interesting chemical properties due to the presence of the methoxyphenyl and ethylidene groups in its structure.

Upstream product

• 70078-14-7 1-(1-diazoethyl)-4-methoxybenzene 
• 56-23-5 tetrachloromethane 
• 6310-14-1 4'-methoxyacetophenone hydrazone 
• 32117-52-5 1-(1-(4-methoxyphenyl)ethylidene)-2-tosylhydrazine 
• 354-48-3 1,1,1-tribromotrifluoroethane 
• 100-06-1 1-(4-methoxyphenyl)ethanone 

Downstream Products

• 100-06-1 1-(4-methoxyphenyl)ethanone 
• 78049-09-9 cis-1-methyl-1,2-di-p-anisylcyclopropane 
• 78049-09-9 trans-1-methyl-1,2-p-anisylcyclopropane 
• 104-93-8 p-methylanizole 
• 1712-69-2 1-isopropenyl-4-methoxybenzene 
• 104-45-0 4-n-propylanisole 
• 4132-48-3 1-methoxy-4-(1-methylethyl)benzene 
• 23263-96-9 3-methyl-5-p-methoxyphenyl-1-hydropyrazole 
• 100-66-3 methoxybenzene 
• 767-00-0 4-cyanophenol 
• 874-90-8 4-methoxybenzonitrile 
• 99-93-4 4-Hydroxyacetophenone 
• 121-97-1 4-Methoxypropiophenone 
• 108-95-2 phenol 

Relevant articles and documents

Cs2CO3-mediated decomposition of N-tosylhydrazones for the synthesis of azines under mild conditions

Abstract: A facile, environmentally and efficient Cs2CO3-mediated decomposition of N-tosylhydrazones reaction has been developed for the synthesis of functionalized azines under mild conditions. This method offers broad substrate scope, occurs as additive-free, without strong base conditions, utilizes readily available reactants, and forms products in good to high yields. Graphical Abstract: [Figure not available: see fulltext.]

Base and solvent mediated decomposition of tosylhydrazones: Highly selective synthesis of N-alkyl substituted hydrazones, dialkylidenehydrazines, and oximes

Base and solvent mediated decomposition of tosylhydrazones was studied. It was found that reaction of tosylhydrazones in CH3NO2 in the presence of 1 equiv of K2CO3 in 90 °C gave N-alkylated products in 52-96% yield. However, when the same reaction was carried out in mixed solvent of CH3NO2 and dioxane in the presence of 3 equiv of NaOH at 110 °C, dialkylidenehydrazines were obtained in moderate to high yield. If the reaction was carried out in mixed solvent of CH3NO2 and DMSO in the presence of 10 equiv of NaOH at 110 °C, CH3NO2 can act as the precursor of hydroxylamine and corresponding oximes were formed in up to 92% yield.

Catalytic olefination of carbonyl compounds. Effect of the structure of the carbonyl compound on the reaction

The mechanism of the novel reaction of catalytic olefination of carbonyl compounds was studied. The reaction involves the transformation of hydrazones of aromatic aldehydes and ketones into the corresponding dichloroalkenes and symmetrical azines by the treatment with carbon tetrachloride in the presence of CuCl as a catalyst. The stability of intermediate diazoalkanes is the main factor determining the direction of the reaction. In the case of sufficiently stable diazoalkanes, other products can be formed under the reaction conditions along with the products of catalytic olefination.