214342-03-7

Upstream product

• 531515-01-2 (E)-ethyl (4S,5S)-4,5-dihydroxy-6-(4-methoxybenzyloxy)-hex-2-enoate 
• 129083-15-4 {(2S,3R)-3-[(4R,5S)-5-(4-Methoxy-benzyloxymethyl)-2,2-dimethyl-[1,3]dioxolan-4-yl]-oxiranyl}-methanol 
• 132352-49-9 ethyl (E)-3-((4S,5S)-5-((4-methoxybenzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)acrylate 
• 132352-47-7 (E)-3-((4S,5S)-5-((4-ethoxybenzyloxy)methyl)-2,2-dimethyl-1,3-dioxolan-4-yl)prop-2-en-1-ol 
• 100-46-9 benzylamine 

Downstream Products

• 19130-96-2 1,5-dideoxy-1,5-imino-D-glucitol 
• 72458-46-9 N-benzyl-1-deoxynojirimycin 
• 214342-01-5 (3aS,6R,7R,7aS)-5-Benzyl-6-hydroxymethyl-2,2-dimethyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-ol 
• 214342-00-4 (3aS,6R,7R,7aS)-5-Benzyl-2,2-dimethyl-6-vinyl-hexahydro-[1,3]dioxolo[4,5-c]pyridin-7-ol 

Relevant academic research and scientific papers

Asymmetric synthesis of (+)-1-deoxynojirimycin

An asymmetric synthesis of (+)-1-deoxynojirimycin (1) in 14 steps starting from diene (5) is described. The key transformations in the sequence are a sharpless dihydroxylation and epoxidation followed by a regio- and stereoselective aminolysis of vinyl epoxide 11 to give piperidine 12.