2146-36-3 Usage
Uses
Perhydroacenaphthene or dodecahydroacenaphthylene is used in the synthesis of Alkyladamantanes by the passage of the latter over the alumina catalyst in a flow-type plant with a metal reactor that has application in the field of nanotechnology.
Preparation
Perhydro acenaphthene is the main raw material of preparation 1,3-dimethyladamantane, is the important intermediate of preparation Derivatives of Adamantane.Derivatives of Adamantane is a kind of excellent antidementia agent, clinical research confirmation its have good efficacy to vascular dementia.The synthesis of Perhydroacenaphthene:1) adding industrial acenaphthylene to 95% ethanol, heating, refluxing and dissolving, then cooling, crystallizing, centrifuging to obtain refined acenaphthene, and carrying out distillation recycling of the filtrate;2) adding the refined acenaphthene and a catalyst Raney Ni into a high-pressure kettle, replacing gas in the kettle with hydrogen, filling hydrogen to make the pressure in the kettle rise to 0.8 MPa, heating up to about 180 DEG C, starting a reaction for 5 h, continuously supplementing hydrogen during the reaction, making the pressure in the kettle rise slowly, and allowing the pressure after the reaction to be 4.0 MPa; 3) cooling after the reaction is finished, filtering the catalyst, and thus obtaining the perhydroacenaphthene.https://patents.google.com/patent/CN105461499A/en
Check Digit Verification of cas no
The CAS Registry Mumber 2146-36-3 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,1,4 and 6 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 2146-36:
(6*2)+(5*1)+(4*4)+(3*6)+(2*3)+(1*6)=63
63 % 10 = 3
So 2146-36-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H20/c1-3-9-4-2-6-11-8-7-10(5-1)12(9)11/h9-12H,1-8H2
2146-36-3Relevant articles and documents
Vapor pressure and liquid heat capacity of perhydroacenaphthylene and perhydrophenanthrene
Rohac, Vladislav,Censky, Miroslav,Zala, Diana,Ruzicka, Vlastimil,Ruzicka, Kvetoslav,Sporka, Karel,Aim, Karel
, p. 1205 - 1210 (2000)
Saturated vapor pressures and liquid heat capacities have been measured for liquid perhydroacenaphthylene and perhydrophenanthrene by comparative ebulliometry over an approximate pressure range from (8 to 100) kPa and by heat conduction calorimetry over a temperature range from about (305 to 335) K. The obtained results for vapor pressures and for heat capacities have been represented within experimental uncertainties by the Antoine and the Cox equations and by an empirical polynomial equation, respectively, and compared with the data available in the literature.
A PROCESS FOR PREPARING MEMANTINE
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Page/Page column 20, (2010/08/08)
The present invention relates to a process for preparing memantine, or a pharmaceutically acceptable salt thereof (e.g., memantine hydrochloride), which is substantially free of impurities.
