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Benzonitrile, 4-acetyl-2-fluoro(9CI), also known as 4-acetyl-2-fluorobenzonitrile, is a chemical compound that belongs to the class of organic compounds known as benzonitriles. These are aromatic compounds containing a benzenoid ring which bears at least one cyano group. It is known for its aromaticity and the presence of a cyano group. As with all chemicals, it should be handled with care and appropriate safety measures should be taken to avoid any harm or adverse reactions. These can include risks such as skin and eye irritation, or more serious health issues if ingested or inhaled.

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  • 214760-18-6 Structure
  • Basic information

    1. Product Name: Benzonitrile, 4-acetyl-2-fluoro- (9CI)
    2. Synonyms: Benzonitrile, 4-acetyl-2-fluoro- (9CI);4-ACETYL-2-FLUOROBENZONITRILE;Benzonitrile,4-acetyl-2-fluoro-;4'-Cyano-3'-fluoroacetophenone
    3. CAS NO:214760-18-6
    4. Molecular Formula: C9H6FNO
    5. Molecular Weight: 163.1484432
    6. EINECS: N/A
    7. Product Categories: HALIDE;ACETYLGROUP
    8. Mol File: 214760-18-6.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 296.2±25.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: /
    5. Density: 1.21±0.1 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Benzonitrile, 4-acetyl-2-fluoro- (9CI)(CAS DataBase Reference)
    10. NIST Chemistry Reference: Benzonitrile, 4-acetyl-2-fluoro- (9CI)(214760-18-6)
    11. EPA Substance Registry System: Benzonitrile, 4-acetyl-2-fluoro- (9CI)(214760-18-6)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 214760-18-6(Hazardous Substances Data)

214760-18-6 Usage

Uses

Unfortunately, the provided materials do not contain any information about the specific uses of Benzonitrile, 4-acetyl-2-fluoro(9CI). Therefore, it is not possible to list its applications and reasons for use in different industries based on the given information.

Check Digit Verification of cas no

The CAS Registry Mumber 214760-18-6 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 2,1,4,7,6 and 0 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 214760-18:
(8*2)+(7*1)+(6*4)+(5*7)+(4*6)+(3*0)+(2*1)+(1*8)=116
116 % 10 = 6
So 214760-18-6 is a valid CAS Registry Number.

214760-18-6SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 15, 2017

Revision Date: Aug 15, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-Acetyl-2-fluorobenzonitrile

1.2 Other means of identification

Product number -
Other names 4-cyano-3-fluoroacetophenone

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:214760-18-6 SDS

214760-18-6Relevant articles and documents

NOVEL BENZIMIDAMIDES COMPOUNDS COMPRISING AN OXABORININ RING

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, (2019/12/28)

The invention relates to 4-(1-hydroxy-3,4-dihydro-1H-benzo[c][1,2]oxaborinin-3-yl)benzimidamide derivatives and their use in treating diseases and conditions of the skin (for example, Netherton syndrome, rosacea, atopic dermatitis, psoriasis and itch) cau

THIAZALOPYRROLIDINE INHIBITORS OF ROR-GAMMA

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, (2014/11/13)

Provided are novel compounds of Formula (I): pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, which are useful in the treatment of diseases and disorders mediated by ROR?. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I) and methods for their use in treating one or more inflammatory, metabolic, autoimmune and other diseases or disorders.

Discovery of selective and potent inhibitors of gram-positive bacterial thymidylate kinase (TMK)

Martínez-Botella, Gabriel,Breen, John N.,Duffy, James E.S.,Dumas, Jacques,Geng, Bolin,Gowers, Ian K.,Green, Oluyinka M.,Guler, Satenig,Hentemann, Martin F.,Hernandez-Juan, Felix A.,Joseph-McCarthy, Diane,Kawatkar, Sameer,Larsen, Nicholas A.,Lazari, Ovadia,Loch, James T.,Macritchie, Jacqueline A.,McKenzie, Andrew R.,Newman, Joseph V.,Olivier, Nelson B.,Otterson, Linda G.,Owens, Andrew P.,Read, Jon,Sheppard, David W.,Keating, Thomas A.

, p. 10010 - 10021 (2013/01/16)

Thymidylate kinase (TMK) is an essential enzyme in bacterial DNA synthesis. The deoxythymidine monophosphate (dTMP) substrate binding pocket was targeted in a rational-design, structure-supported effort, yielding a unique series of antibacterial agents sh

IMIDAZOLE DERIVATIVES USEFUL AS INHIBITORS OF FAAH

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Page/Page column 29, (2010/01/07)

The present invention is directed to certain imidazole derivatives which are useful as inhibitors of Fatty Acid Amide Hydrolase (FAAH). The invention is also concerned with pharmaceutical formulations comprising these compounds as active ingredients and the use of the compounds and their formulations in the treatment of certain disorders, including osteoarthritis, rheumatoid arthritis, diabetic neuropathy, postherpetic neuralgia, skeletomuscular pain, and fibromyalgia, as well as acute pain, migraine, sleep disorder, Alzeimer Disease, and Parkinson's Disease.

Pyrrolidine and related derivatives useful as PR modulators

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Page/Page column 17, (2010/11/30)

Compounds of the following structure are described: wherein R1-R6, R11, R12, m, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compou

Tricyclic oxazolidone derivatives useful as PR modulators

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Page/Page column 17, (2008/06/13)

Compounds of the following structure are described: wherein R1-R6, R16, m, V, W, X, Y, and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are use

Oxazolidone derivatives as PR modulators

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Page/Page column 34, (2008/06/13)

Compounds of the following structure are described: wherein R1, R2, R5, R6, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful for treating a variety of hormone-related conditions including contraception, treating or preventing fibroids, endometriosis, dysfunctional bleeding, uterine leiomyomata, polycystic ovary syndrome, or hormone-dependent carcinomas, providing hormone replacement therapy, stimulating food intake or synchronizing estrus.

Imidazolidin-2-one derivatives useful as PR modulators

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Page/Page column 17, (2010/11/30)

Compounds of the following structure are described: wherein R1-R6, R10, m, V, X, Y, Z and Q are described herein, or a pharmaceutically acceptable salt, tautomer, metabolite or prodrug thereof. These compounds are useful f

Nicotinamide benzofused-heterocyclyl derivatives useful as selective inhibitors of pde4 isozymes

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, (2008/06/13)

Compounds useful as inhibitors of PDE4 in the treatment of diseases regulated by the activation and degranulation of eosinophils, especially asthma, chronic bronchitis, and chronic obstructive pulmonary disease, of Formula (1.0.0): 1 wherein R5 and R6 are

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