21527-61-7

Upstream product

• 67-64-1 acetone 
• 2043-61-0 cyclohexanecarbaldehyde 
• 7152-32-1 4-cyclohexyl-3-buten-2-one 
• 10035-10-6 hydrogen bromide 
• 2316-84-9 4-cyclohexyl-4-hydroxybutan-2-one 
• 7553-56-2 iodine 
• 108-94-1 cyclohexanone 
• 51004-16-1 (2-Methoxy-2-methyl-cyclopropylidene)-cyclohexane 
• 100702-40-7 4-cyclohexylidene-2-methyl-2-(trimethylsiloxy)butanal 

Downstream Products

• 701-98-4 β-cyclohexylidenepropionic acid 
• 124-04-9 Adipic acid 

Relevant academic research and scientific papers

Method for the production of gamma , delta -unsaturated ketones by reacting tertiary allyl alcohols with alkenyl alkyl ethers

PCT No. PCT/EP97/06425 Sec. 371 Date Jan. 29, 1999 Sec. 102(e) Date Jan. 29, 1999 PCT Filed Nov. 18, 1997 PCT Pub. No. WO98/23570 PCT Pub. Date Jun. 4, 1998An improved process is described for preparing gamma , delta -unsaturated ke-tones, which are in demand as aroma substances and intermediates for vitamins and carotenoids, by reacting tertiary allyl alcohols and alkenyl alkyl ethers in the presence of acid catalysts at elevated temperature, which comprises carrying out the reaction in the presence of a phosphorus derivative of the formula IV where A and B are each a branched or unbranched alkyl or alkoxy having from 1 to 10 carbons, a substituted or unsubstituted aryl, cycloalkyl, aryloxy or cycloaryloxy; A can additionally be -H or -OH or A and B together are a substituted or unsubstituted tetramethylene or pentamethylene or substituted or unsubstituted phenyl-1,2-diol or 1,1'-binaphthyl-2,2'-diol.

Regiospecific Synthesis of β, γ-Unsaturated Ketones from Allylic Alcohols. Claisen Rearrangement of α-Allyloxy Ketone Enol Derivatives

β,γ-Unsaturated ketones are prepared with regiospecific C-C bond formation at the former γ-position of primary, secondary, or tertiary allylic alcohol precursors by a process involving sigmatropic Claisen rearrangement of intermediate α-allyloxy ket

REACTIVITE DU DERIVE LITHIE ISSU DU DIOXOLANNE DU LEVULATE DE TRIMETHYLSILYLE VIS-A-VIS DES DERIVES CARBONYLES: UNE METHODE DIRECTE D'OLEFINATION DES ALDEHYDES AROMATIQUES ET DES CETONES

At -60 deg C and in ether, the organolithium reagent produced by trimethylsilyl 4,4-ethylenedioxypentanoate reacts with aldehydes and ketones, and gives the expected β-hydroxyacids.The β-ethylenic ketones are isolated when the condensation is carried out